Clark JW - Search Results

1

Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer.

Singh H, Keller RB, Kapner KS, Dilly J, Raghavan S, Yuan C, Cohen EF, Tolstorukov M, Andrews E, Brais LK, da Silva A, Perez K, Rubinson DA, Surana R, Giannakis M, Ng K, Clancy TE, Yurgelun MB, Schlechter BL, Clark JW, Shapiro GI, Rosenthal MH, Hornick JL, Nardi V, Li YY, Gupta H, Cherniack AD, Meyerson M, Cleary JM, Nowak JA, Wolpin BM, Aguirre AJ. Singh H, et al. Among authors: clark jw. Clin Cancer Res. 2023 Nov 14;29(22):4627-4643. doi: 10.1158/1078-0432.CCR-22-3930. Clin Cancer Res. 2023. PMID: 37463056

2

Phase I clinical trial and pharmacokinetic study of the spicamycin analog KRN5500 administered as a 1-hour intravenous infusion for five consecutive days to patients with refractory solid tumors.

Supko JG, Eder JP Jr, Ryan DP, Seiden MV, Lynch TJ, Amrein PC, Kufe DW, Clark JW. Supko JG, et al. Among authors: clark jw. Clin Cancer Res. 2003 Nov 1;9(14):5178-86. Clin Cancer Res. 2003. PMID: 14613997 Clinical Trial.

3

Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors.

Clark JW, Eder JP, Ryan D, Lathia C, Lenz HJ. Clark JW, et al. Clin Cancer Res. 2005 Aug 1;11(15):5472-80. doi: 10.1158/1078-0432.CCR-04-2658. Clin Cancer Res. 2005. PMID: 16061863 Clinical Trial.

4

Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.

Ogino S, Meyerhardt JA, Cantor M, Brahmandam M, Clark JW, Namgyal C, Kawasaki T, Kinsella K, Michelini AL, Enzinger PC, Kulke MH, Ryan DP, Loda M, Fuchs CS. Ogino S, et al. Among authors: clark jw. Clin Cancer Res. 2005 Sep 15;11(18):6650-6. doi: 10.1158/1078-0432.CCR-05-0738. Clin Cancer Res. 2005. PMID: 16166444 Clinical Trial.

5

Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas.

Kwak EL, Jankowski J, Thayer SP, Lauwers GY, Brannigan BW, Harris PL, Okimoto RA, Haserlat SM, Driscoll DR, Ferry D, Muir B, Settleman J, Fuchs CS, Kulke MH, Ryan DP, Clark JW, Sgroi DC, Haber DA, Bell DW. Kwak EL, et al. Among authors: clark jw. Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4283-7. doi: 10.1158/1078-0432.CCR-06-0189. Clin Cancer Res. 2006. PMID: 16857803 Free PMC article.

6

Phase I study of gefitinib plus FOLFIRI in previously untreated patients with metastatic colorectal cancer.

Wolpin BM, Clark JW, Meyerhardt JA, Earle CC, Ryan DP, Enzinger PC, Zhu AX, Blaszkowsky L, Battu S, Fuchs CS. Wolpin BM, et al. Among authors: clark jw. Clin Colorectal Cancer. 2006 Sep;6(3):208-13. doi: 10.3816/CCC.2006.n.037. Clin Colorectal Cancer. 2006. PMID: 17026790 Clinical Trial.

7

CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.

Ogino S, Meyerhardt JA, Kawasaki T, Clark JW, Ryan DP, Kulke MH, Enzinger PC, Wolpin BM, Loda M, Fuchs CS. Ogino S, et al. Among authors: clark jw. Virchows Arch. 2007 May;450(5):529-37. doi: 10.1007/s00428-007-0398-3. Epub 2007 Mar 20. Virchows Arch. 2007. PMID: 17372756

8

Targeted agents: the rules of combination.

Kwak EL, Clark JW, Chabner B. Kwak EL, et al. Among authors: clark jw. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5232-7. doi: 10.1158/1078-0432.CCR-07-1385. Clin Cancer Res. 2007. PMID: 17875749 Review.

9

Trends in the use and role of biomarkers in phase I oncology trials.

Goulart BH, Clark JW, Pien HH, Roberts TG, Finkelstein SN, Chabner BA. Goulart BH, et al. Among authors: clark jw. Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6719-26. doi: 10.1158/1078-0432.CCR-06-2860. Clin Cancer Res. 2007. PMID: 18006773 Review.

10

Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.

Wolpin BM, Hezel AF, Abrams T, Blaszkowsky LS, Meyerhardt JA, Chan JA, Enzinger PC, Allen B, Clark JW, Ryan DP, Fuchs CS. Wolpin BM, et al. Among authors: clark jw. J Clin Oncol. 2009 Jan 10;27(2):193-8. doi: 10.1200/JCO.2008.18.9514. Epub 2008 Dec 1. J Clin Oncol. 2009. PMID: 19047305 Free PMC article. Clinical Trial.

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