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BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.
Vohhodina J, Goehring LJ, Liu B, Kong Q, Botchkarev VV Jr, Huynh M, Liu Z, Abderazzaq FO, Clark AP, Ficarro SB, Marto JA, Hatchi E, Livingston DM. Vohhodina J, et al. Among authors: clark ap. Nat Commun. 2021 Jun 10;12(1):3542. doi: 10.1038/s41467-021-23716-6. Nat Commun. 2021. PMID: 34112789 Free PMC article.
BRCA1 pathway function in basal-like breast cancer cells.
Hill SJ, Clark AP, Silver DP, Livingston DM. Hill SJ, et al. Among authors: clark ap. Mol Cell Biol. 2014 Oct;34(20):3828-42. doi: 10.1128/MCB.01646-13. Epub 2014 Aug 4. Mol Cell Biol. 2014. PMID: 25092866 Free PMC article.
Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.
Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, Beroukhim R, Marto JA, Vidal M, Gaudet S, Hill DE, Livingston DM. Hill SJ, et al. Among authors: clark ap. Genes Dev. 2014 Sep 1;28(17):1957-75. doi: 10.1101/gad.241620.114. Genes Dev. 2014. PMID: 25184681 Free PMC article.
MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy.
Neupane M, Clark AP, Landini S, Birkbak NJ, Eklund AC, Lim E, Culhane AC, Barry WT, Schumacher SE, Beroukhim R, Szallasi Z, Vidal M, Hill DE, Silver DP. Neupane M, et al. Among authors: clark ap. Cancer Discov. 2016 Jan;6(1):45-58. doi: 10.1158/2159-8290.CD-15-0341. Epub 2015 Nov 6. Cancer Discov. 2016. PMID: 26546296 Free PMC article.
Logic-based modeling of biological networks with Netflux.
Clark AP, Chowkwale M, Paap A, Dang S, Saucerman JJ. Clark AP, et al. bioRxiv [Preprint]. 2024 Jan 15:2024.01.11.575227. doi: 10.1101/2024.01.11.575227. bioRxiv. 2024. PMID: 38293087 Free PMC article. Preprint.
137 results