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Taming the SARS-CoV-2-mediated proinflammatory response with BromAc®.
Ferreira GM, Clarindo FA, Ribeiro ÁL, Gomes-de-Pontes L, de Carvalho LD, Martins-Filho OA, da Fonseca FG, Teixeira MM, Sabino AP, Eapen MS, Morris DL, Valle SJ, Coelho-Dos-Reis JGA. Ferreira GM, et al. Among authors: clarindo fa. Front Immunol. 2023 Dec 13;14:1308477. doi: 10.3389/fimmu.2023.1308477. eCollection 2023. Front Immunol. 2023. PMID: 38193087 Free PMC article.
New anti-SARS-CoV-2 aminoadamantane compounds as antiviral candidates for the treatment of COVID-19.
de Almeida Marques DP, Andrade LAF, Reis EVS, Clarindo FA, Moraes TFS, Lourenço KL, De Barros WA, Costa NEM, Andrade LM, Lopes-Ribeiro Á, Coêlho Maciel MS, Corrêa-Dias LC, de Almeida IN, Arantes TS, Litwinski VCV, de Oliveira LC, Serafim MSM, Maltarollo VG, Guatimosim SC, Silva MM, Tsuji M, Ferreira RS, Barreto LV, Barbosa-Stancioli EF, da Fonseca FG, De Fátima Â, Coelho-Dos-Reis JGA. de Almeida Marques DP, et al. Among authors: clarindo fa. Virus Res. 2024 Feb;340:199291. doi: 10.1016/j.virusres.2023.199291. Epub 2023 Dec 14. Virus Res. 2024. PMID: 38065303 Free PMC article.
Synthesis of cannabidiol-based compounds as ACE2 inhibitors with potential application in the treatment of COVID-19.
Marques GVL, Marques DPA, Clarindo FA, Avendaño-Villarreal JA, Guerra FS, Fernandes PD, Dos Santos EN, Gusevskaya EV, Kohlhoff M, Moreira FA, Andrade LAF, Fonseca FGD, Dos-Reis JGAC, Oliveira RB. Marques GVL, et al. Among authors: clarindo fa. Eur J Med Chem. 2023 Nov 15;260:115760. doi: 10.1016/j.ejmech.2023.115760. Epub 2023 Aug 28. Eur J Med Chem. 2023. PMID: 37657273
Ex-vivo mucolytic and anti-inflammatory activity of BromAc in tracheal aspirates from COVID-19.
Coelho Dos Reis JGA, Ferreira GM, Lourenço AA, Ribeiro ÁL, da Mata CPDSM, de Melo Oliveira P, Marques DPA, Ferreira LL, Clarindo FA, da Silva MF, Filho HPP, Oliveira NRR Jr, Sodré MMD, Gadelha SR, Albuquerque GR, Maciel BM, Mariano APM, Silva MM, Fontana R, Marin LJ, Carlos RSA, Lopes ATS, Ferreira FB, Dos Santos UR, Santana ÍTS, Fehlberg HF, Rezende RP, Dias JCT, Gross E, Goulart GAC, Santiago MG, de Lemos APML, da Conceição AO, Romano CC, de Carvalho LD, Martins Filho OA, Quadros CA, Morris DL, Valle SJ. Coelho Dos Reis JGA, et al. Among authors: clarindo fa. Biomed Pharmacother. 2022 Apr;148:112753. doi: 10.1016/j.biopha.2022.112753. Epub 2022 Feb 25. Biomed Pharmacother. 2022. PMID: 35272139 Free PMC article.