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Design, stereoselective synthesis, configurational stability and biological activity of 7-chloro-9-(furan-3-yl)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide.
Carrozzo MM, Battisti UM, Cannazza G, Puia G, Ravazzini F, Falchicchio A, Perrone S, Citti C, Jozwiak K, Braghiroli D, Parenti C, Troisi L. Carrozzo MM, et al. Among authors: citti c. Bioorg Med Chem. 2014 Sep 1;22(17):4667-76. doi: 10.1016/j.bmc.2014.07.017. Epub 2014 Jul 18. Bioorg Med Chem. 2014. PMID: 25126714 Free article.
7-Chloro-5-(furan-3-yl)-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-Dioxide as Positive Allosteric Modulator of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor. The End of the Unsaturated-Inactive Paradigm?
Citti C, Battisti UM, Cannazza G, Jozwiak K, Stasiak N, Puja G, Ravazzini F, Ciccarella G, Braghiroli D, Parenti C, Troisi L, Zoli M. Citti C, et al. ACS Chem Neurosci. 2016 Feb 17;7(2):149-60. doi: 10.1021/acschemneuro.5b00257. Epub 2015 Dec 2. ACS Chem Neurosci. 2016. PMID: 26580317
"Heart-cut" bidimensional achiral-chiral liquid chromatography applied to the evaluation of stereoselective metabolism, in vivo biological activity and brain response to chiral drug candidates targeting the central nervous system.
Battisti UM, Citti C, Larini M, Ciccarella G, Stasiak N, Troisi L, Braghiroli D, Parenti C, Zoli M, Cannazza G. Battisti UM, et al. Among authors: citti c. J Chromatogr A. 2016 Apr 22;1443:152-61. doi: 10.1016/j.chroma.2016.03.027. Epub 2016 Mar 14. J Chromatogr A. 2016. PMID: 27020886
Probing an Allosteric Pocket of CDK2 with Small Molecules.
Christodoulou MS, Caporuscio F, Restelli V, Carlino L, Cannazza G, Costanzi E, Citti C, Lo Presti L, Pisani P, Battistutta R, Broggini M, Passarella D, Rastelli G. Christodoulou MS, et al. Among authors: citti c. ChemMedChem. 2017 Jan 5;12(1):33-41. doi: 10.1002/cmdc.201600474. Epub 2016 Dec 19. ChemMedChem. 2017. PMID: 27860401
135 results