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The N-terminal cysteine is a dual sensor of oxygen and oxidative stress.
Heo AJ, Kim SB, Ji CH, Han D, Lee SJ, Lee SH, Lee MJ, Lee JS, Ciechanover A, Kim BY, Kwon YT. Heo AJ, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2107993118. doi: 10.1073/pnas.2107993118. Proc Natl Acad Sci U S A. 2021. PMID: 34893540 Free PMC article.
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
Ciechanover A, DiGiuseppe JA, Bercovich B, Orian A, Richter JD, Schwartz AL, Brodeur GM. Ciechanover A, et al. Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):139-43. doi: 10.1073/pnas.88.1.139. Proc Natl Acad Sci U S A. 1991. PMID: 1846034 Free PMC article.
Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.
Gonen H, Smith CE, Siegel NR, Kahana C, Merrick WC, Chakraburtty K, Schwartz AL, Ciechanover A. Gonen H, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7648-52. doi: 10.1073/pnas.91.16.7648. Proc Natl Acad Sci U S A. 1994. PMID: 8052636 Free PMC article.
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
Zaaroor-Regev D, de Bie P, Scheffner M, Noy T, Shemer R, Heled M, Stein I, Pikarsky E, Ciechanover A. Zaaroor-Regev D, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6788-93. doi: 10.1073/pnas.1003108107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351251 Free PMC article.
Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT. Cha-Molstad H, et al. Among authors: ciechanover a. Nat Cell Biol. 2015 Jul;17(7):917-29. doi: 10.1038/ncb3177. Epub 2015 Jun 15. Nat Cell Biol. 2015. PMID: 26075355 Free PMC article.
302 results