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N-Acylethanolamine acid amidase (NAAA) is dysregulated in colorectal cancer patients and its inhibition reduces experimental cancer growth.
Romano B, Pagano E, Iannotti FA, Piscitelli F, Brancaleone V, Lucariello G, Nanì MF, Fiorino F, Sparaco R, Vanacore G, Di Tella F, Cicia D, Lionetti R, Makriyannis A, Malamas M, De Luca M, Aprea G, D'Armiento M, Capasso R, Sbarro B, Venneri T, Di Marzo V, Borrelli F, Izzo AA. Romano B, et al. Among authors: cicia d. Br J Pharmacol. 2022 Apr;179(8):1679-1694. doi: 10.1111/bph.15737. Epub 2021 Dec 28. Br J Pharmacol. 2022. PMID: 34791641 Free PMC article.
TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β-catenin signalling.
Pagano E, Romano B, Cicia D, Iannotti FA, Venneri T, Lucariello G, Nanì MF, Cattaneo F, De Cicco P, D'Armiento M, De Luca M, Lionetti R, Lama S, Stiuso P, Zoppoli P, Falco G, Marchianò S, Fiorucci S, Capasso R, Di Marzo V, Borrelli F, Izzo AA. Pagano E, et al. Among authors: cicia d. Br J Pharmacol. 2023 Jan;180(2):235-251. doi: 10.1111/bph.15960. Epub 2022 Oct 17. Br J Pharmacol. 2023. PMID: 36168728 Free PMC article.
11 results