Cichońska A - Search Results

1

Crowdsourced mapping of unexplored target space of kinase inhibitors.

Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM; IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium; Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G, Wennerberg K, Guinney J, Aittokallio T. Cichońska A, et al. Nat Commun. 2021 Jun 3;12(1):3307. doi: 10.1038/s41467-021-23165-1. Nat Commun. 2021. PMID: 34083538 Free PMC article.

2

Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors.

Cichonska A, Ravikumar B, Parri E, Timonen S, Pahikkala T, Airola A, Wennerberg K, Rousu J, Aittokallio T. Cichonska A, et al. PLoS Comput Biol. 2017 Aug 7;13(8):e1005678. doi: 10.1371/journal.pcbi.1005678. eCollection 2017 Aug. PLoS Comput Biol. 2017. PMID: 28787438 Free PMC article.

3

Identification of drug candidates and repurposing opportunities through compound-target interaction networks.

Cichonska A, Rousu J, Aittokallio T. Cichonska A, et al. Expert Opin Drug Discov. 2015 Dec;10(12):1333-45. doi: 10.1517/17460441.2015.1096926. Epub 2015 Oct 1. Expert Opin Drug Discov. 2015. PMID: 26429153 Review.

4

Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects.

Julkunen H, Cichonska A, Gautam P, Szedmak S, Douat J, Pahikkala T, Aittokallio T, Rousu J. Julkunen H, et al. Among authors: cichonska a. Nat Commun. 2020 Dec 1;11(1):6136. doi: 10.1038/s41467-020-19950-z. Nat Commun. 2020. PMID: 33262326 Free PMC article.

5

Learning with multiple pairwise kernels for drug bioactivity prediction.

Cichonska A, Pahikkala T, Szedmak S, Julkunen H, Airola A, Heinonen M, Aittokallio T, Rousu J. Cichonska A, et al. Bioinformatics. 2018 Jul 1;34(13):i509-i518. doi: 10.1093/bioinformatics/bty277. Bioinformatics. 2018. PMID: 29949975 Free PMC article.

6

Modeling drug combination effects via latent tensor reconstruction.

Wang T, Szedmak S, Wang H, Aittokallio T, Pahikkala T, Cichonska A, Rousu J. Wang T, et al. Among authors: cichonska a. Bioinformatics. 2021 Jul 12;37(Suppl_1):i93-i101. doi: 10.1093/bioinformatics/btab308. Bioinformatics. 2021. PMID: 34252952 Free PMC article.

7

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy.

Honeyborne I, McHugh TD, Kuittinen I, Cichonska A, Evangelopoulos D, Ronacher K, van Helden PD, Gillespie SH, Fernandez-Reyes D, Walzl G, Rousu J, Butcher PD, Waddell SJ. Honeyborne I, et al. Among authors: cichonska a. BMC Med. 2016 Apr 7;14:68. doi: 10.1186/s12916-016-0609-3. BMC Med. 2016. PMID: 27055815 Free PMC article.

8

metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis.

Cichonska A, Rousu J, Marttinen P, Kangas AJ, Soininen P, Lehtimäki T, Raitakari OT, Järvelin MR, Salomaa V, Ala-Korpela M, Ripatti S, Pirinen M. Cichonska A, et al. Bioinformatics. 2016 Jul 1;32(13):1981-9. doi: 10.1093/bioinformatics/btw052. Epub 2016 Feb 19. Bioinformatics. 2016. PMID: 27153689 Free PMC article.

MOTIVATION: A dominant approach to genetic association studies is to perform univariate tests between genotype-phenotype pairs. ...Currently, modest sample sizes of individual cohorts, and restricted availability of individual-level genotype-phenotype data across the cohor …

MOTIVATION: A dominant approach to genetic association studies is to perform univariate tests between genotype-phenotype pairs. ...Cu …

9

Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population.

Julkunen H, Cichońska A, Slagboom PE, Würtz P; Nightingale Health UK Biobank Initiative. Julkunen H, et al. Among authors: cichonska a. Elife. 2021 May 4;10:e63033. doi: 10.7554/eLife.63033. Elife. 2021. PMID: 33942721 Free PMC article.

10

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation.

Smith CJ, Sinnott-Armstrong N, Cichońska A, Julkunen H, Fauman EB, Würtz P, Pritchard JK. Smith CJ, et al. Among authors: cichonska a. Elife. 2022 Sep 8;11:e79348. doi: 10.7554/eLife.79348. Elife. 2022. PMID: 36073519 Free PMC article.

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