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Poly(ADP-Ribose) Polymerase Inhibitors for Arsenic Trioxide-Resistant Acute Promyelocytic Leukemia: Synergistic In Vitro Antitumor Effects with Hypomethylating Agents or High-Dose Vitamin C.
Giansanti M, De Gabrieli A, Prete SP, Ottone T, Divona MD, Karimi T, Ciccarone F, Voso MT, Graziani G, Faraoni I. Giansanti M, et al. Among authors: ciccarone f. J Pharmacol Exp Ther. 2021 Jun;377(3):385-397. doi: 10.1124/jpet.121.000537. Epub 2021 Apr 5. J Pharmacol Exp Ther. 2021. PMID: 33820831
Poly(ADP-ribosyl)ation affects stabilization of Che-1 protein in response to DNA damage.
Bacalini MG, Di Lonardo D, Catizone A, Ciccarone F, Bruno T, Zampieri M, Guastafierro T, Calabrese R, Fanciulli M, Passananti C, Caiafa P, Reale A. Bacalini MG, et al. Among authors: ciccarone f. DNA Repair (Amst). 2011 Apr 3;10(4):380-9. doi: 10.1016/j.dnarep.2011.01.002. Epub 2011 Feb 12. DNA Repair (Amst). 2011. PMID: 21317046
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
Bamezai S, Demir D, Pulikkottil AJ, Ciccarone F, Fischbein E, Sinha A, Borga C, Te Kronnie G, Meyer LH, Mohr F, Götze M, Caiafa P, Debatin KM, Döhner K, Döhner H, González-Menéndez I, Quintanilla-Fend L, Herold T, Jeremias I, Feuring-Buske M, Buske C, Rawat VPS. Bamezai S, et al. Among authors: ciccarone f. Leukemia. 2021 Feb;35(2):389-403. doi: 10.1038/s41375-020-0864-3. Epub 2020 May 15. Leukemia. 2021. PMID: 32409690
122 results