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Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.
Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ. Zhang H, et al. Among authors: church g. Cancer Discov. 2020 Feb;10(2):288-305. doi: 10.1158/2159-8290.CD-19-0811. Epub 2019 Nov 26. Cancer Discov. 2020. PMID: 31771969 Free PMC article.
A second-generation M1-polarized CAR macrophage with antitumor efficacy.
Lei A, Yu H, Lu S, Lu H, Ding X, Tan T, Zhang H, Zhu M, Tian L, Wang X, Su S, Xue D, Zhang S, Zhao W, Chen Y, Xie W, Zhang L, Zhu Y, Zhao J, Jiang W, Church G, Chan FK, Gao Z, Zhang J. Lei A, et al. Among authors: church g. Nat Immunol. 2024 Jan;25(1):102-116. doi: 10.1038/s41590-023-01687-8. Epub 2023 Nov 27. Nat Immunol. 2024. PMID: 38012418
Single-Cell CRISPR-Based Lineage Tracing in Mice.
Kalhor K, Church GM. Kalhor K, et al. Biochemistry. 2019 Dec 3;58(48):4775-4776. doi: 10.1021/acs.biochem.9b00688. Epub 2019 Nov 15. Biochemistry. 2019. PMID: 31730337 Free PMC article.
Precise Cas9 targeting enables genomic mutation prevention.
Chavez A, Pruitt BW, Tuttle M, Shapiro RS, Cecchi RJ, Winston J, Turczyk BM, Tung M, Collins JJ, Church GM. Chavez A, et al. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3669-3673. doi: 10.1073/pnas.1718148115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555762 Free PMC article.
Rapid in vitro production of single-stranded DNA.
Minev D, Guerra R, Kishi JY, Smith C, Krieg E, Said K, Hornick A, Sasaki HM, Filsinger G, Beliveau BJ, Yin P, Church GM, Shih WM. Minev D, et al. Among authors: church gm. Nucleic Acids Res. 2019 Dec 16;47(22):11956-11962. doi: 10.1093/nar/gkz998. Nucleic Acids Res. 2019. PMID: 31713635 Free PMC article.
694 results