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Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST.
Schaefer IM, Hemming ML, Lundberg MZ, Serrata MP, Goldaracena I, Liu N, Yin P, Paulo JA, Gygi SP, George S, Morgan JA, Bertagnolli MM, Sicinska ET, Chu C, Zheng S, Mariño-Enríquez A, Hornick JL, Raut CP, Ou WB, Demetri GD, Saka SK, Fletcher JA. Schaefer IM, et al. Among authors: chu c. Br J Cancer. 2022 Nov;127(11):2072-2085. doi: 10.1038/s41416-022-01990-5. Epub 2022 Sep 29. Br J Cancer. 2022. PMID: 36175617 Free PMC article.
USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice.
Dang F, Bai L, Dong J, Hu X, Wang J, Paulo JA, Xiong Y, Liang X, Sun Y, Chen Y, Guo M, Wang X, Huang Z, Inuzuka H, Chen L, Chu C, Liu J, Zhang T, Rezaeian AH, Liu J, Kaniskan HÜ, Zhong B, Zhang J, Letko M, Jin J, Lan K, Wei W. Dang F, et al. Among authors: chu c. Sci Transl Med. 2023 Dec 6;15(725):eadh7668. doi: 10.1126/scitranslmed.adh7668. Epub 2023 Dec 6. Sci Transl Med. 2023. PMID: 38055802
Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells.
Michowski W, Chick JM, Chu C, Kolodziejczyk A, Wang Y, Suski JM, Abraham B, Anders L, Day D, Dunkl LM, Li Cheong Man M, Zhang T, Laphanuwat P, Bacon NA, Liu L, Fassl A, Sharma S, Otto T, Jecrois E, Han R, Sweeney KE, Marro S, Wernig M, Geng Y, Moses A, Li C, Gygi SP, Young RA, Sicinski P. Michowski W, et al. Among authors: chu c. Mol Cell. 2020 May 7;78(3):459-476.e13. doi: 10.1016/j.molcel.2020.03.010. Epub 2020 Apr 1. Mol Cell. 2020. PMID: 32240602 Free PMC article.
Cyclin E in normal physiology and disease states.
Chu C, Geng Y, Zhou Y, Sicinski P. Chu C, et al. Trends Cell Biol. 2021 Sep;31(9):732-746. doi: 10.1016/j.tcb.2021.05.001. Epub 2021 May 27. Trends Cell Biol. 2021. PMID: 34052101 Free PMC article. Review.
The requirement for cyclin E in c-Myc overexpressing breast cancers.
Zhou Y, Geng Y, Zhang Y, Zhou Y, Chu C, Sharma S, Fassl A, Butter D, Sicinski P. Zhou Y, et al. Among authors: chu c. Cell Cycle. 2020 Oct;19(20):2589-2599. doi: 10.1080/15384101.2020.1804720. Epub 2020 Sep 25. Cell Cycle. 2020. PMID: 32975478 Free PMC article.
Small Noncoding RNAs in Reproduction and Infertility.
Zhu Q, Kirby JA, Chu C, Gou LT. Zhu Q, et al. Among authors: chu c. Biomedicines. 2021 Dec 12;9(12):1884. doi: 10.3390/biomedicines9121884. Biomedicines. 2021. PMID: 34944700 Free PMC article. Review.
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy.
Gao Y, Nihira NT, Bu X, Chu C, Zhang J, Kolodziejczyk A, Fan Y, Chan NT, Ma L, Liu J, Wang D, Dai X, Liu H, Ono M, Nakanishi A, Inuzuka H, North BJ, Huang YH, Sharma S, Geng Y, Xu W, Liu XS, Li L, Miki Y, Sicinski P, Freeman GJ, Wei W. Gao Y, et al. Among authors: chu c. Nat Cell Biol. 2020 Sep;22(9):1064-1075. doi: 10.1038/s41556-020-0562-4. Epub 2020 Aug 24. Nat Cell Biol. 2020. PMID: 32839551 Free PMC article.
8,418 results