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Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism.
Front Drug Discov (Lausanne). 2022 Jan;1:818003. doi: 10.3389/fddsv.2021.818003. Epub 2022 Jan 14.
Front Drug Discov (Lausanne). 2022.
PMID: 35237767
Free PMC article.
Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP1-23.
Apostol CR, Tanguturi P, Szabò LZ, Varela D, Gilmartin T, Streicher JM, Polt R.
Apostol CR, et al.
Molecules. 2021 Aug 14;26(16):4932. doi: 10.3390/molecules26164932.
Molecules. 2021.
PMID: 34443519
Free PMC article.
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Glycopeptide drugs: A pharmacological dimension between "Small Molecules" and "Biologics".
Apostol CR, Hay M, Polt R.
Apostol CR, et al.
Peptides. 2020 Sep;131:170369. doi: 10.1016/j.peptides.2020.170369. Epub 2020 Jul 13.
Peptides. 2020.
PMID: 32673700
Free PMC article.
Review.
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Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain.
Giri AK, Apostol CR, Wang Y, Forte BL, Largent-Milnes TM, Davis P, Rankin D, Molnar G, Olson KM, Porreca F, Vanderah TW, Hruby VJ.
Giri AK, et al. Among authors: apostol cr.
J Med Chem. 2015 Nov 12;58(21):8573-83. doi: 10.1021/acs.jmedchem.5b01170. Epub 2015 Oct 30.
J Med Chem. 2015.
PMID: 26465170
Free PMC article.
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