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Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension.
Li Q, Barrett A, Vijayakrishnan B, Tiberghien A, Beard R, Rickert KW, Allen KL, Christie RJ, Marelli M, Harper J, Howard P, Wu H, Dall'Acqua WF, Tsui P, Gao C, Borrok MJ. Li Q, et al. Among authors: christie rj. Bioconjug Chem. 2019 Apr 17;30(4):1232-1243. doi: 10.1021/acs.bioconjchem.9b00170. Epub 2019 Apr 3. Bioconjug Chem. 2019. PMID: 30912649
Tuning the Diels-Alder Reaction for Bioconjugation to Maleimide Drug-Linkers.
St Amant AH, Lemen D, Florinas S, Mao S, Fazenbaker C, Zhong H, Wu H, Gao C, Christie RJ, Read de Alaniz J. St Amant AH, et al. Among authors: christie rj. Bioconjug Chem. 2018 Jul 18;29(7):2406-2414. doi: 10.1021/acs.bioconjchem.8b00320. Epub 2018 Jun 22. Bioconjug Chem. 2018. PMID: 29932647
A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.
St Amant AH, Huang F, Lin J, Lemen D, Chakiath C, Mao S, Fazenbaker C, Zhong H, Harper J, Xu W, Patel N, Adams L, Vijayakrishnan B, Howard PW, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ. St Amant AH, et al. Among authors: christie rj. Bioconjug Chem. 2019 Sep 18;30(9):2340-2348. doi: 10.1021/acs.bioconjchem.9b00436. Epub 2019 Aug 19. Bioconjug Chem. 2019. PMID: 31380623
A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments.
Florinas S, Liu M, Fleming R, Van Vlerken-Ysla L, Ayriss J, Gilbreth R, Dimasi N, Gao C, Wu H, Xu ZQ, Chen S, Dirisala A, Kataoka K, Cabral H, Christie RJ. Florinas S, et al. Among authors: christie rj. Biomacromolecules. 2016 May 9;17(5):1818-33. doi: 10.1021/acs.biomac.6b00239. Epub 2016 Apr 4. Biomacromolecules. 2016. PMID: 27007881
Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer.
Bosco EE, Christie RJ, Carrasco R, Sabol D, Zha J, DaCosta K, Brown L, Kennedy M, Meekin J, Phipps S, Ayriss J, Du Q, Bezabeh B, Chowdhury P, Breen S, Chen C, Reed M, Hinrichs M, Zhong H, Xiao Z, Dixit R, Herbst R, Tice DA. Bosco EE, et al. Among authors: christie rj. Oncotarget. 2018 May 1;9(33):22960-22975. doi: 10.18632/oncotarget.25160. eCollection 2018 May 1. Oncotarget. 2018. PMID: 29796165 Free PMC article.
71 results