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Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults.
Kalantar KL, Neyton L, Abdelghany M, Mick E, Jauregui A, Caldera S, Serpa PH, Ghale R, Albright J, Sarma A, Tsitsiklis A, Leligdowicz A, Christenson SA, Liu K, Kangelaris KN, Hendrickson C, Sinha P, Gomez A, Neff N, Pisco A, Doernberg SB, Derisi JL, Matthay MA, Calfee CS, Langelier CR. Kalantar KL, et al. Among authors: christenson sa. Nat Microbiol. 2022 Nov;7(11):1805-1816. doi: 10.1038/s41564-022-01237-2. Epub 2022 Oct 20. Nat Microbiol. 2022. PMID: 36266337 Free PMC article. Clinical Trial.
A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD.
DiLillo KM, Norman KC, Freeman CM, Christenson SA, Alexis NE, Anderson WH, Barjaktarevic IZ, Barr RG, Comellas AP, Bleecker ER, Boucher RC, Couper DJ, Criner GJ, Doerschuk CM, Wells JM, Han MK, Hoffman EA, Hansel NN, Hastie AT, Kaner RJ, Krishnan JA, Labaki WW, Martinez FJ, Meyers DA, O'Neal WK, Ortega VE, Paine R 3rd, Peters SP, Woodruff PG, Cooper CB, Bowler RP, Curtis JL, Arnold KB; SPIROMICS investigators. DiLillo KM, et al. Among authors: christenson sa. Sci Rep. 2023 May 22;13(1):8228. doi: 10.1038/s41598-023-32216-0. Sci Rep. 2023. PMID: 37217548 Free PMC article.
IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma.
Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG. Bhakta NR, et al. Among authors: christenson sa. Am J Respir Crit Care Med. 2018 Feb 1;197(3):313-324. doi: 10.1164/rccm.201706-1070OC. Am J Respir Crit Care Med. 2018. PMID: 29064281 Free PMC article.
Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.
Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Langelier C, et al. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12353-E12362. doi: 10.1073/pnas.1809700115. Epub 2018 Nov 27. Proc Natl Acad Sci U S A. 2018. PMID: 30482864 Free PMC article.
Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2.
Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Calfee CS, Castañeda G, DeRisi JL, Detweiler AM, Hao S, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Christenson SA, Kistler A, Langelier C. Mick E, et al. Among authors: christenson sa. medRxiv [Preprint]. 2020 May 19:2020.05.18.20105171. doi: 10.1101/2020.05.18.20105171. medRxiv. 2020. PMID: 32511476 Free PMC article. Updated. Preprint.
Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses.
Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Castañeda G, DeRisi JL, Detweiler AM, Hao SL, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Calfee CS, Christenson SA, Kistler A, Langelier C. Mick E, et al. Among authors: christenson sa. Nat Commun. 2020 Nov 17;11(1):5854. doi: 10.1038/s41467-020-19587-y. Nat Commun. 2020. PMID: 33203890 Free PMC article.
COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone.
Sarma A, Christenson SA, Mick E, DeVoe C, Deiss T, Pisco AO, Ghale R, Jauregui A, Byrne A, Moazed F, Spottiswoode N, Sinha P, Zha BS, Neff N, Tan M, Serpa PH, Ansel KM, Wilson JG, Leligdowicz A, Siegel ER, Sirota M, DeRisi JL, Matthay MA; COMET Consortium; Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Calfee CS, Langelier CR. Sarma A, et al. Among authors: christenson sa. Res Sq [Preprint]. 2021 Jan 14:rs.3.rs-141578. doi: 10.21203/rs.3.rs-141578/v1. Res Sq. 2021. PMID: 33469573 Free PMC article. Updated. Preprint.
100 results