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Microscopy imaging of liposomes: from coverslips to environmental SEM.
Bibi S, Kaur R, Henriksen-Lacey M, McNeil SE, Wilkhu J, Lattmann E, Christensen D, Mohammed AR, Perrie Y. Bibi S, et al. Among authors: christensen d. Int J Pharm. 2011 Sep 30;417(1-2):138-50. doi: 10.1016/j.ijpharm.2010.12.021. Epub 2010 Dec 21. Int J Pharm. 2011. PMID: 21182914 Review.
Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses.
Davidsen J, Rosenkrands I, Christensen D, Vangala A, Kirby D, Perrie Y, Agger EM, Andersen P. Davidsen J, et al. Among authors: christensen d. Biochim Biophys Acta. 2005 Dec 10;1718(1-2):22-31. doi: 10.1016/j.bbamem.2005.10.011. Epub 2005 Nov 14. Biochim Biophys Acta. 2005. PMID: 16321607 Free article.
alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying.
Christensen D, Kirby D, Foged C, Agger EM, Andersen P, Perrie Y, Nielsen HM. Christensen D, et al. Biochim Biophys Acta. 2008 May;1778(5):1365-73. doi: 10.1016/j.bbamem.2008.01.013. Epub 2008 Jan 26. Biochim Biophys Acta. 2008. PMID: 18261458 Free article.
In previous experiments we have shown that trehalose is able to protect a non-phospholipid-based liposomal adjuvant (designated CAF01) composed of the cationic dimethyldioctadecylammonium (DDA) and trehalose 6,6'-dibehenate (TDB) during freeze-drying [D. Christensen …
In previous experiments we have shown that trehalose is able to protect a non-phospholipid-based liposomal adjuvant (designated CAF01) compo …
Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response.
Henriksen-Lacey M, Christensen D, Bramwell VW, Lindenstrøm T, Agger EM, Andersen P, Perrie Y. Henriksen-Lacey M, et al. Among authors: christensen d. J Control Release. 2010 Jul 14;145(2):102-8. doi: 10.1016/j.jconrel.2010.03.027. Epub 2010 Apr 8. J Control Release. 2010. PMID: 20381556
Comparison of the depot effect and immunogenicity of liposomes based on dimethyldioctadecylammonium (DDA), 3β-[N-(N',N'-Dimethylaminoethane)carbomyl] cholesterol (DC-Chol), and 1,2-Dioleoyl-3-trimethylammonium propane (DOTAP): prolonged liposome retention mediates stronger Th1 responses.
Henriksen-Lacey M, Christensen D, Bramwell VW, Lindenstrøm T, Agger EM, Andersen P, Perrie Y. Henriksen-Lacey M, et al. Among authors: christensen d. Mol Pharm. 2011 Feb 7;8(1):153-61. doi: 10.1021/mp100208f. Epub 2010 Dec 15. Mol Pharm. 2011. PMID: 21117621
Liposomal vaccine delivery systems.
Henriksen-Lacey M, Korsholm KS, Andersen P, Perrie Y, Christensen D. Henriksen-Lacey M, et al. Among authors: christensen d. Expert Opin Drug Deliv. 2011 Apr;8(4):505-19. doi: 10.1517/17425247.2011.558081. Epub 2011 Mar 18. Expert Opin Drug Deliv. 2011. PMID: 21413904 Review.
A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog.
Christensen D, Henriksen-Lacey M, Kamath AT, Lindenstrøm T, Korsholm KS, Christensen JP, Rochat AF, Lambert PH, Andersen P, Siegrist CA, Perrie Y, Agger EM. Christensen D, et al. Among authors: christensen jp. J Control Release. 2012 Jun 28;160(3):468-76. doi: 10.1016/j.jconrel.2012.03.016. Epub 2012 Mar 27. J Control Release. 2012. PMID: 22709414
1,142 results