Critical role of IL-1α in IL-1β-induced inflammatory responses: cooperation with NF-κBp65 in transcriptional regulation.
Singh AK, Fechtner S, Chourasia M, Sicalo J, Ahmed S.
Singh AK, et al. Among authors: chourasia m.
FASEB J. 2019 Feb;33(2):2526-2536. doi: 10.1096/fj.201801513R. Epub 2018 Oct 1.
FASEB J. 2019.
PMID: 30272996
Free PMC article.
Our study highlights the importance of IL-1alpha in mediating IL-1beta-induced inflammation in addition to maintaining its expression and providing a rationale for targeting IL-1alpha to minimize the role of IL-1beta in inflammatory diseases like RA.-Singh, A. K., Fechtner, S., …
Our study highlights the importance of IL-1alpha in mediating IL-1beta-induced inflammation in addition to maintaining its expression and pr …