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Development and Applications of Chimera Platforms for Tyrosine Phosphorylation.
Pergu R, Shoba VM, Chaudhary SK, Munkanatta Godage DNP, Deb A, Singha S, Dhawa U, Singh P, Anokhina V, Singh S, Siriwardena SU, Choudhary A. Pergu R, et al. Among authors: choudhary a. ACS Cent Sci. 2023 Aug 9;9(8):1558-1566. doi: 10.1021/acscentsci.3c00200. eCollection 2023 Aug 23. ACS Cent Sci. 2023. PMID: 37637727 Free PMC article.
A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9.
Maji B, Gangopadhyay SA, Lee M, Shi M, Wu P, Heler R, Mok B, Lim D, Siriwardena SU, Paul B, Dančík V, Vetere A, Mesleh MF, Marraffini LA, Liu DR, Clemons PA, Wagner BK, Choudhary A. Maji B, et al. Among authors: choudhary a. Cell. 2019 May 2;177(4):1067-1079.e19. doi: 10.1016/j.cell.2019.04.009. Cell. 2019. PMID: 31051099 Free PMC article.
Phosphorylation-Inducing Chimeric Small Molecules.
Siriwardena SU, Munkanatta Godage DNP, Shoba VM, Lai S, Shi M, Wu P, Chaudhary SK, Schreiber SL, Choudhary A. Siriwardena SU, et al. Among authors: choudhary a. J Am Chem Soc. 2020 Aug 19;142(33):14052-14057. doi: 10.1021/jacs.0c05537. Epub 2020 Aug 4. J Am Chem Soc. 2020. PMID: 32787262
Chemical and optical control of CRISPR-associated nucleases.
Modell AE, Siriwardena SU, Shoba VM, Li X, Choudhary A. Modell AE, et al. Among authors: choudhary a. Curr Opin Chem Biol. 2021 Feb;60:113-121. doi: 10.1016/j.cbpa.2020.10.003. Epub 2020 Nov 27. Curr Opin Chem Biol. 2021. PMID: 33253976 Review.
Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes.
Sreekanth V, Zhou Q, Kokkonda P, Bermudez-Cabrera HC, Lim D, Law BK, Holmes BR, Chaudhary SK, Pergu R, Leger BS, Walker JA, Gifford DK, Sherwood RI, Choudhary A. Sreekanth V, et al. Among authors: choudhary a. ACS Cent Sci. 2020 Dec 23;6(12):2228-2237. doi: 10.1021/acscentsci.0c00129. Epub 2020 Nov 18. ACS Cent Sci. 2020. PMID: 33376784 Free PMC article.
Rational Design of Silicon-Based Zinc Ionophores.
Yamada K, Deb A, Shoba VM, Lim D, Maji B, Modell AE, Choudhary A. Yamada K, et al. Among authors: choudhary a. Angew Chem Int Ed Engl. 2022 Jun 7;61(23):e202201698. doi: 10.1002/anie.202201698. Epub 2022 Apr 6. Angew Chem Int Ed Engl. 2022. PMID: 35385189 Free PMC article.
Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins.
Shoba VM, Munkanatta Godage DNP, Chaudhary SK, Deb A, Siriwardena SU, Choudhary A. Shoba VM, et al. Among authors: choudhary a. Angew Chem Int Ed Engl. 2022 Jul 18;61(29):e202202770. doi: 10.1002/anie.202202770. Epub 2022 May 31. Angew Chem Int Ed Engl. 2022. PMID: 35641438 Free PMC article.
A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules.
Lim D, Zhou Q, Cox KJ, Law BK, Lee M, Kokkonda P, Sreekanth V, Pergu R, Chaudhary SK, Gangopadhyay SA, Maji B, Lai S, Amako Y, Thompson DB, Subramanian HKK, Mesleh MF, Dančík V, Clemons PA, Wagner BK, Woo CM, Church GM, Choudhary A. Lim D, et al. Among authors: choudhary a. Nat Cell Biol. 2022 Dec;24(12):1766-1775. doi: 10.1038/s41556-022-01005-8. Epub 2022 Nov 17. Nat Cell Biol. 2022. PMID: 36396978 Free PMC article.
Proximity-inducing modalities: the past, present, and future.
Singh S, Tian W, Severance ZC, Chaudhary SK, Anokhina V, Mondal B, Pergu R, Singh P, Dhawa U, Singha S, Choudhary A. Singh S, et al. Among authors: choudhary a. Chem Soc Rev. 2023 Aug 14;52(16):5485-5515. doi: 10.1039/d2cs00943a. Chem Soc Rev. 2023. PMID: 37477631 Review.
1,085 results