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Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
Otsuka Y, Airola MV, Choi YM, Coant N, Snider J, Cariello C, Saied EM, Arenz C, Bannister T, Rahaim R Jr, Hannun YA, Shumate J, Scampavia L, Haley JD, Spicer TP. Otsuka Y, et al. Among authors: choi ym. SLAS Discov. 2021 Jan;26(1):113-121. doi: 10.1177/2472555220945283. Epub 2020 Jul 31. SLAS Discov. 2021. PMID: 32734807 Free PMC article.
The middle lipin domain adopts a membrane-binding dimeric protein fold.
Gu W, Gao S, Wang H, Fleming KD, Hoffmann RM, Yang JW, Patel NM, Choi YM, Burke JE, Reue K, Airola MV. Gu W, et al. Among authors: choi ym. Nat Commun. 2021 Aug 5;12(1):4718. doi: 10.1038/s41467-021-24929-5. Nat Commun. 2021. PMID: 34354069 Free PMC article.
Measurement of neutral ceramidase activity in vitro and in vivo.
Simoes M, Saleh A, Choi YM, Airola MV, Haley JD, Coant N. Simoes M, et al. Among authors: choi ym. Anal Biochem. 2022 Apr 15;643:114577. doi: 10.1016/j.ab.2022.114577. Epub 2022 Feb 5. Anal Biochem. 2022. PMID: 35134389 Review.
[No title available]
[No authors listed] [No authors listed] PMID: 35554488
Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Coant N, Bickel JD, Rahaim R, Otsuka Y, Choi YM, Xu R, Simoes M, Cariello C, Mao C, Saied EM, Arenz C, Spicer TP, Bannister TD, Tonge PJ, Airola MV, Scampavia L, Hannun YA, Rizzo RC, Haley JD. Coant N, et al. Among authors: choi ym. Bioorg Chem. 2023 Oct;139:106747. doi: 10.1016/j.bioorg.2023.106747. Epub 2023 Jul 27. Bioorg Chem. 2023. PMID: 37531819 Free PMC article.
Corrigendum to "Comprehensive evaluation of nutritional components, bioactive metabolites, and antioxidant activities in diverse sorghum (Sorghum bicolor (L.) Moench) landraces" [Food Res. Int. 173(Part 2) (2023) 113390].
Desta KT, Choi YM, Shin MJ, Yoon H, Wang X, Lee Y, Yi J, Jeon YA, Lee S. Desta KT, et al. Among authors: choi ym. Food Res Int. 2024 Jun;185:114132. doi: 10.1016/j.foodres.2024.114132. Epub 2024 Feb 19. Food Res Int. 2024. PMID: 38658066 No abstract available.
692 results