Choi HG - Search Results

1

Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and Angiogenesis.

Han Y, Sengupta S, Lee BJ, Cho H, Kim J, Choi HG, Dash U, Kim JH, Kim ND, Kim JH, Sim T. Han Y, et al. Among authors: choi hg. J Med Chem. 2019 Oct 24;62(20):9141-9160. doi: 10.1021/acs.jmedchem.9b01025. Epub 2019 Oct 7. J Med Chem. 2019. PMID: 31513411

2

Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277.

Cho H, Sengupta S, Jeon SS, Hur W, Choi HG, Seo HS, Lee BJ, Kim JH, Chung M, Jeon NL, Kim ND, Sim T. Cho H, et al. Among authors: choi hg. J Med Chem. 2017 Feb 23;60(4):1495-1508. doi: 10.1021/acs.jmedchem.6b01679. Epub 2017 Feb 6. J Med Chem. 2017. PMID: 28103025

3

First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.

Cho H, Shin I, Ju E, Choi S, Hur W, Kim H, Hong E, Kim ND, Choi HG, Gray NS, Sim T. Cho H, et al. Among authors: choi hg, choi s. J Med Chem. 2018 Sep 27;61(18):8353-8373. doi: 10.1021/acs.jmedchem.8b00882. Epub 2018 Sep 11. J Med Chem. 2018. PMID: 30153003

4

Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3.

Cho H, Shin I, Yoon H, Jeon E, Lee J, Kim Y, Ryu S, Song C, Kwon NH, Moon Y, Kim S, Kim ND, Choi HG, Sim T. Cho H, et al. Among authors: choi hg. J Med Chem. 2021 Aug 26;64(16):11934-11957. doi: 10.1021/acs.jmedchem.1c00459. Epub 2021 Jul 29. J Med Chem. 2021. PMID: 34324343

5

Discovery of Inhibitors That Overcome the G1202R Anaplastic Lymphoma Kinase Resistance Mutation.

Hatcher JM, Bahcall M, Choi HG, Gao Y, Sim T, George R, Jänne PA, Gray NS. Hatcher JM, et al. Among authors: choi hg. J Med Chem. 2015 Dec 10;58(23):9296-9308. doi: 10.1021/acs.jmedchem.5b01136. Epub 2015 Nov 25. J Med Chem. 2015. PMID: 26568289 Free PMC article.

6

X-ray Crystal Structure-Guided Design and Optimization of 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor.

Lee Y, Kim H, Kim H, Cho HY, Jee JG, Seo KA, Son JB, Ko E, Choi HG, Kim ND, Kim I. Lee Y, et al. Among authors: choi hg. J Med Chem. 2021 May 27;64(10):6985-6995. doi: 10.1021/acs.jmedchem.1c00542. Epub 2021 May 4. J Med Chem. 2021. PMID: 33942608

7

Covalent Guanosine Mimetic Inhibitors of G12C KRAS.

Xiong Y, Lu J, Hunter J, Li L, Scott D, Choi HG, Lim SM, Manandhar A, Gondi S, Sim T, Westover KD, Gray NS. Xiong Y, et al. Among authors: choi hg. ACS Med Chem Lett. 2016 Nov 30;8(1):61-66. doi: 10.1021/acsmedchemlett.6b00373. eCollection 2017 Jan 12. ACS Med Chem Lett. 2016. PMID: 28105276 Free PMC article.

8

Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability.

Liu Q, Wang J, Kang SA, Thoreen CC, Hur W, Choi HG, Waller DL, Sim T, Sabatini DM, Gray NS. Liu Q, et al. Among authors: choi hg. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4036-40. doi: 10.1016/j.bmcl.2011.04.129. Epub 2011 May 7. Bioorg Med Chem Lett. 2011. PMID: 21621413 Free PMC article.

9

Development of 'DFG-out' inhibitors of gatekeeper mutant kinases.

Choi HG, Zhang J, Weisberg E, Griffin JD, Sim T, Gray NS. Choi HG, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5297-302. doi: 10.1016/j.bmcl.2012.06.036. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22819762 Free PMC article.

10

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones.

Deng X, Elkins JM, Zhang J, Yang Q, Erazo T, Gomez N, Choi HG, Wang J, Dzamko N, Lee JD, Sim T, Kim N, Alessi DR, Lizcano JM, Knapp S, Gray NS. Deng X, et al. Among authors: choi hg. Eur J Med Chem. 2013;70:758-67. doi: 10.1016/j.ejmech.2013.10.052. Epub 2013 Oct 29. Eur J Med Chem. 2013. PMID: 24239623 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

1,099 results

Search Page