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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.
Khattar E, Maung KZY, Chew CL, Ghosh A, Mok MMH, Lee P, Zhang J, Chor WHJ, Cildir G, Wang CQ, Mohd-Ismail NK, Chin DWL, Lee SC, Yang H, Shin YJ, Nam DH, Chen L, Kumar AP, Deng LW, Ikawa M, Gunaratne J, Osato M, Tergaonkar V. Khattar E, et al. Among authors: chin dwl. Nat Commun. 2019 Dec 13;10(1):5349. doi: 10.1038/s41467-019-13082-9. Nat Commun. 2019. PMID: 31836706 Free PMC article.
Aged healthy mice acquire clonal hematopoiesis mutations.
Chin DWL, Yoshizato T, Virding Culleton S, Grasso F, Barbachowska M, Ogawa S, Jacobsen SEW, Woll PS. Chin DWL, et al. Blood. 2022 Jan 27;139(4):629-634. doi: 10.1182/blood.2021014235. Blood. 2022. PMID: 34665864 Free PMC article.
Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.
Duarte S, Woll PS, Buza-Vidas N, Chin DWL, Boukarabila H, Luís TC, Stenson L, Bouriez-Jones T, Ferry H, Mead AJ, Atkinson D, Jin S, Clark SA, Wu B, Repapi E, Gray N, Taylor S, Mutvei AP, Tsoi YL, Nerlov C, Lendahl U, Jacobsen SEW. Duarte S, et al. Among authors: chin dwl. Blood. 2018 Apr 12;131(15):1712-1719. doi: 10.1182/blood-2017-06-788505. Epub 2018 Jan 16. Blood. 2018. PMID: 29339402 Free PMC article.
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.
Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T, Lehmann S, Jacobsen SEW, Woll PS, Olweus J. Giannakopoulou E, et al. Among authors: chin dwl. Nat Cancer. 2023 Oct;4(10):1474-1490. doi: 10.1038/s43018-023-00642-8. Epub 2023 Oct 2. Nat Cancer. 2023. PMID: 37783807 Free PMC article.
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.
Wojtowicz EE, Mistry JJ, Uzun V, Hellmich C, Scoones A, Chin DW, Kettyle LM, Grasso F, Lord AM, Wright DJ, Etherington GJ, Woll PS, Belderbos ME, Bowles KM, Nerlov C, Haerty W, Bystrykh LV, Jacobsen SEW, Rushworth SA, Macaulay IC. Wojtowicz EE, et al. Genome Biol. 2023 Jun 27;24(1):152. doi: 10.1186/s13059-023-02976-z. Genome Biol. 2023. PMID: 37370129 Free PMC article.
15 results