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Effects of the Soluble Guanylate Cyclase Stimulator Praliciguat in Diabetic Kidney Disease: A Randomized Placebo-Controlled Clinical Trial.
Clin J Am Soc Nephrol. 2020 Dec 31;16(1):59-69. doi: 10.2215/CJN.08410520. Epub 2020 Dec 16.
Clin J Am Soc Nephrol. 2020.
PMID: 33328269
Free PMC article.
Clinical Trial.
A Randomized, Placebo-Controlled, Multiple-Ascending-Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Soluble Guanylate Cyclase Stimulator Praliciguat in Healthy Subjects.
Hanrahan JP, Wakefield JD, Wilson PJ, Mihova M, Chickering JG, Ruff D, Hall M, Milne GT, Currie MG, Profy AT.
Hanrahan JP, et al. Among authors: chickering jg.
Clin Pharmacol Drug Dev. 2019 Jul;8(5):564-575. doi: 10.1002/cpdd.627. Epub 2018 Nov 13.
Clin Pharmacol Drug Dev. 2019.
PMID: 30422390
Clinical Trial.
Item in Clipboard
An exploratory, randomised, placebo-controlled, 14 day trial of the soluble guanylate cyclase stimulator praliciguat in participants with type 2 diabetes and hypertension.
Hanrahan JP, Seferovic JP, Wakefield JD, Wilson PJ, Chickering JG, Jung J, Carlson KE, Zimmer DP, Frelinger AL 3rd, Michelson AD, Morrow L, Hall M, Currie MG, Milne GT, Profy AT.
Hanrahan JP, et al. Among authors: chickering jg.
Diabetologia. 2020 Apr;63(4):733-743. doi: 10.1007/s00125-019-05062-x. Epub 2019 Dec 19.
Diabetologia. 2020.
PMID: 31858186
Free PMC article.
Clinical Trial.
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Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease.
Zimmer DP, Shea CM, Tobin JV, Tchernychev B, Germano P, Sykes K, Banijamali AR, Jacobson S, Bernier SG, Sarno R, Carvalho A, Chien YT, Graul R, Buys ES, Jones JE, Wakefield JD, Price GM, Chickering JG, Milne GT, Currie MG, Masferrer JL.
Zimmer DP, et al. Among authors: chickering jg.
Front Pharmacol. 2020 Apr 8;11:419. doi: 10.3389/fphar.2020.00419. eCollection 2020.
Front Pharmacol. 2020.
PMID: 32322204
Free PMC article.
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Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential.
Buys ES, Zimmer DP, Chickering J, Graul R, Chien YT, Profy A, Hadcock JR, Masferrer JL, Milne GT.
Buys ES, et al.
Nitric Oxide. 2018 Aug 1;78:72-80. doi: 10.1016/j.niox.2018.05.009. Epub 2018 May 31.
Nitric Oxide. 2018.
PMID: 29859918
Free article.
Review.
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The impact of abdominal pain on global measures in patients with chronic idiopathic constipation, before and after treatment with linaclotide: a pooled analysis of two randomised, double-blind, placebo-controlled, phase 3 trials.
Chang L, Lembo AJ, Lavins BJ, Shiff SJ, Hao X, Chickering JG, Jia XD, Currie MG, Kurtz CB, Johnston JM.
Chang L, et al. Among authors: chickering jg.
Aliment Pharmacol Ther. 2014 Dec;40(11-12):1302-12. doi: 10.1111/apt.12985. Epub 2014 Oct 13.
Aliment Pharmacol Ther. 2014.
PMID: 25312449
Free PMC article.
Clinical Trial.
Item in Clipboard
Innervation of propatagial musculature in a flying squirrel, Glaucomys volans (Rodentia, Sciuridae).
Chickering JG, Sokoloff AJ.
Chickering JG, et al.
Brain Behav Evol. 1996;47(1):1-7. doi: 10.1159/000113224.
Brain Behav Evol. 1996.
PMID: 8834780
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