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Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins.
Taiana E, Bandini C, Favasuli VK, Ronchetti D, Silvestris I, Puccio N, Todoerti K, Erratico S, Giannandrea D, Bolli N, Amodio N, Ciarrocchi A, Chiaramonte R, Torrente Y, Piva R, Neri A. Taiana E, et al. Among authors: chiaramonte r. Haematologica. 2023 Jan 1;108(1):219-233. doi: 10.3324/haematol.2022.281167. Haematologica. 2023. PMID: 36073514 Free PMC article.
Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line.
Verdelli D, Nobili L, Todoerti K, Mosca L, Fabris S, D'Anca M, Pellegrino E, Piva R, Inghirami G, Capelli C, Introna M, Baldini L, Chiaramonte R, Lombardi L, Neri A. Verdelli D, et al. Among authors: chiaramonte r. Genes Chromosomes Cancer. 2014 Feb;53(2):154-67. doi: 10.1002/gcc.22127. Epub 2013 Nov 5. Genes Chromosomes Cancer. 2014. PMID: 24327544
Notch signaling drives multiple myeloma induced osteoclastogenesis.
Colombo M, Thümmler K, Mirandola L, Garavelli S, Todoerti K, Apicella L, Lazzari E, Lancellotti M, Platonova N, Akbar M, Chiriva-Internati M, Soutar R, Neri A, Goodyear CS, Chiaramonte R. Colombo M, et al. Among authors: chiaramonte r. Oncotarget. 2014 Nov 15;5(21):10393-406. doi: 10.18632/oncotarget.2084. Oncotarget. 2014. PMID: 25257302 Free PMC article.
PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation.
Platonova N, Manzo T, Mirandola L, Colombo M, Calzavara E, Vigolo E, Cermisoni GC, De Simone D, Garavelli S, Cecchinato V, Lazzari E, Neri A, Chiaramonte R. Platonova N, et al. Among authors: chiaramonte r. Genes Chromosomes Cancer. 2015 Aug;54(8):516-526. doi: 10.1002/gcc.22264. Epub 2015 Jun 6. Genes Chromosomes Cancer. 2015. PMID: 26052821
Notch signaling deregulation in multiple myeloma: A rational molecular target.
Colombo M, Galletti S, Garavelli S, Platonova N, Paoli A, Basile A, Taiana E, Neri A, Chiaramonte R. Colombo M, et al. Among authors: chiaramonte r. Oncotarget. 2015 Sep 29;6(29):26826-40. doi: 10.18632/oncotarget.5025. Oncotarget. 2015. PMID: 26308486 Free PMC article. Review.
Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche.
Colombo M, Galletti S, Bulfamante G, Falleni M, Tosi D, Todoerti K, Lazzari E, Crews LA, Jamieson CH, Ravaioli S, Baccianti F, Garavelli S, Platonova N, Neri A, Chiaramonte R. Colombo M, et al. Among authors: chiaramonte r. Oncotarget. 2016 Aug 30;7(35):56013-56029. doi: 10.18632/oncotarget.10820. Oncotarget. 2016. PMID: 27463014 Free PMC article.
Targeting Notch as a Therapeutic Approach for Human Malignancies.
Platonova N, Lesma E, Basile A, Bignotto M, Garavelli S, Palano MT, Moschini A, Neri A, Colombo M, Chiaramonte R. Platonova N, et al. Among authors: chiaramonte r. Curr Pharm Des. 2017;23(1):108-134. doi: 10.2174/1381612822666161006160524. Curr Pharm Des. 2017. PMID: 27719637 Review.
Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma-Enhanced Angiogenesis: A Novel Therapeutic Target?
Saltarella I, Frassanito MA, Lamanuzzi A, Brevi A, Leone P, Desantis V, Di Marzo L, Bellone M, Derudas D, Ribatti D, Chiaramonte R, Palano MT, Neri A, Mariggiò MA, Fumarulo R, Dammacco F, Racanelli V, Vacca A, Ria R. Saltarella I, et al. Among authors: chiaramonte r. Neoplasia. 2019 Jan;21(1):93-105. doi: 10.1016/j.neo.2018.10.011. Epub 2018 Dec 5. Neoplasia. 2019. PMID: 30529074 Free PMC article.
125 results