Chhabra S - Search Results

1

Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.

Belgi A, Burnley JV, MacRaild CA, Chhabra S, Elnahriry KA, Robinson SD, Gooding SG, Tae HS, Bartels P, Sadeghi M, Zhao FY, Wei H, Spanswick D, Adams DJ, Norton RS, Robinson AJ. Belgi A, et al. Among authors: chhabra s. J Med Chem. 2021 Mar 25;64(6):3222-3233. doi: 10.1021/acs.jmedchem.0c02151. Epub 2021 Mar 16. J Med Chem. 2021. PMID: 33724033

2

Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets.

Chhabra S, Belgi A, Bartels P, van Lierop BJ, Robinson SD, Kompella SN, Hung A, Callaghan BP, Adams DJ, Robinson AJ, Norton RS. Chhabra S, et al. J Med Chem. 2014 Dec 11;57(23):9933-44. doi: 10.1021/jm501126u. Epub 2014 Dec 1. J Med Chem. 2014. PMID: 25393758

3

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent.

Yap BK, Leung EW, Yagi H, Galea CA, Chhabra S, Chalmers DK, Nicholson SE, Thompson PE, Norton RS. Yap BK, et al. Among authors: chhabra s. J Med Chem. 2014 Aug 28;57(16):7006-15. doi: 10.1021/jm500596j. Epub 2014 Aug 6. J Med Chem. 2014. PMID: 25068993

4

Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.

Green BR, Zhang MM, Chhabra S, Robinson SD, Wilson MJ, Redding A, Olivera BM, Yoshikami D, Bulaj G, Norton RS. Green BR, et al. Among authors: chhabra s. FEBS J. 2014 Jul;281(13):2885-98. doi: 10.1111/febs.12835. Epub 2014 Jun 9. FEBS J. 2014. PMID: 24814369 Free PMC article.

5

A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin Fold.

Robinson SD, Chhabra S, Belgi A, Chittoor B, Safavi-Hemami H, Robinson AJ, Papenfuss AT, Purcell AW, Norton RS. Robinson SD, et al. Among authors: chhabra s. Structure. 2016 Feb 2;24(2):293-9. doi: 10.1016/j.str.2015.11.015. Epub 2016 Jan 7. Structure. 2016. PMID: 26774129 Free article.

6

Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ.

Green BR, Gajewiak J, Chhabra S, Skalicky JJ, Zhang MM, Rivier JE, Bulaj G, Olivera BM, Yoshikami D, Norton RS. Green BR, et al. Among authors: chhabra s. J Biol Chem. 2016 Mar 25;291(13):7205-20. doi: 10.1074/jbc.M115.697672. Epub 2016 Jan 27. J Biol Chem. 2016. PMID: 26817840 Free PMC article.

7

Stereoselective synthesis and structural elucidation of dicarba peptides.

Gleeson EC, Wang ZJ, Robinson SD, Chhabra S, MacRaild CA, Jackson WR, Norton RS, Robinson AJ. Gleeson EC, et al. Among authors: chhabra s. Chem Commun (Camb). 2016 Mar 25;52(24):4446-9. doi: 10.1039/c5cc10540d. Chem Commun (Camb). 2016. PMID: 26892179

8

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.

Drane SB, Robinson SD, MacRaild CA, Chhabra S, Chittoor B, Morales RA, Leung EW, Belgi A, Espino SS, Olivera BM, Robinson AJ, Chalmers DK, Norton RS. Drane SB, et al. Among authors: chhabra s. Toxicon. 2017 Apr;129:113-122. doi: 10.1016/j.toxicon.2017.02.012. Epub 2017 Feb 17. Toxicon. 2017. PMID: 28216409

9

Reinvestigation of the biological activity of d-allo-ShK protein.

Dang B, Chhabra S, Pennington MW, Norton RS, Kent SBH. Dang B, et al. Among authors: chhabra s. J Biol Chem. 2017 Jul 28;292(30):12599-12605. doi: 10.1074/jbc.M117.793943. Epub 2017 Jun 8. J Biol Chem. 2017. PMID: 28596383 Free PMC article.

10

N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.

Chang SC, Huq R, Chhabra S, Beeton C, Pennington MW, Smith BJ, Norton RS. Chang SC, et al. Among authors: chhabra s. FEBS J. 2015 Jun;282(12):2247-59. doi: 10.1111/febs.13294. Epub 2015 Apr 23. FEBS J. 2015. PMID: 25864722 Free PMC article.

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