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From netrin-1-targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors.
Kryza D, Wischhusen J, Richaud M, Hervieu M, Sidi Boumedine J, Delcros JG, Besse S, Baudier T, Laval PA, Breusa S, Boutault E, Clermidy H, Rama N, Ducarouge B, Devouassoux-Shisheboran M, Chezal JM, Giraudet AL, Walter T, Mehlen P, Sarrut D, Gibert B. Kryza D, et al. Among authors: chezal jm. EMBO Mol Med. 2023 Apr 11;15(4):e16732. doi: 10.15252/emmm.202216732. Epub 2023 Mar 6. EMBO Mol Med. 2023. PMID: 36876343 Free PMC article.
New opportunities with the Duff reaction.
Masurier N, Moreau E, Lartigue C, Gaumet V, Chezal JM, Heitz A, Teulade JC, Chavignon O. Masurier N, et al. Among authors: chezal jm. J Org Chem. 2008 Aug 1;73(15):5989-92. doi: 10.1021/jo800700b. Epub 2008 Jul 3. J Org Chem. 2008. PMID: 18597528
Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.
Trzeciakiewicz A, Fortin S, Moreau E, C-Gaudreault R, Lacroix J, Chambon C, Communal Y, Chezal JM, Miot-Noirault E, Bouchon B, Degoul F. Trzeciakiewicz A, et al. Among authors: chezal jm. Biochem Pharmacol. 2011 May 1;81(9):1116-23. doi: 10.1016/j.bcp.2011.02.014. Epub 2011 Mar 1. Biochem Pharmacol. 2011. PMID: 21371445 Free article.
Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity.
Masurier N, Debiton E, Jacquemet A, Bussière A, Chezal JM, Ollivier A, Tétégan D, Andaloussi M, Galmier MJ, Lacroix J, Canitrot D, Teulade JC, Gaudreault RC, Chavignon O, Moreau E. Masurier N, et al. Among authors: chezal jm. Eur J Med Chem. 2012 Jun;52:137-50. doi: 10.1016/j.ejmech.2012.03.011. Epub 2012 Mar 20. Eur J Med Chem. 2012. PMID: 22503207
Synthesis, radiolabeling and preliminary in vivo evaluation of multimodal radiotracers for PET imaging and targeted radionuclide therapy of pigmented melanoma.
Billaud EM, Maisonial-Besset A, Rbah-Vidal L, Vidal A, Besse S, Béquignat JB, Decombat C, Degoul F, Audin L, Deloye JB, Dollé F, Kuhnast B, Madelmont JC, Tarrit S, Galmier MJ, Borel M, Auzeloux P, Miot-Noirault E, Chezal JM. Billaud EM, et al. Among authors: chezal jm. Eur J Med Chem. 2015 Mar 6;92:818-38. doi: 10.1016/j.ejmech.2015.01.034. Epub 2015 Jan 21. Eur J Med Chem. 2015. PMID: 25637883
92 results