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First clinical-grade porcine kidney xenotransplant using a human decedent model.
Porrett PM, Orandi BJ, Kumar V, Houp J, Anderson D, Cozette Killian A, Hauptfeld-Dolejsek V, Martin DE, Macedon S, Budd N, Stegner KL, Dandro A, Kokkinaki M, Kuravi KV, Reed RD, Fatima H, Killian JT Jr, Baker G, Perry J, Wright ED, Cheung MD, Erman EN, Kraebber K, Gamblin T, Guy L, George JF, Ayares D, Locke JE. Porrett PM, et al. Among authors: cheung md. Am J Transplant. 2022 Apr;22(4):1037-1053. doi: 10.1111/ajt.16930. Epub 2022 Jan 20. Am J Transplant. 2022. PMID: 35049121 Free article.
Spatiotemporal immune atlas of the first clinical-grade, gene-edited pig-to-human kidney xenotransplant.
Cheung MD, Asiimwe R, Erman EN, Fucile CF, Liu S, Sun CW, Hanumanthu VS, Pal HC, Wright ED, Ghajar-Rahimi G, Epstein D, Orandi BJ, Kumar V, Anderson DJ, Greene ME, Bell M, Yates S, Moore KH, LaFontaine J, Killian JT Jr, Baker G, Perry J, Reed R, Little SC, Rosenberg AF, George JF, Locke JE, Porrett PM. Cheung MD, et al. Res Sq [Preprint]. 2023 Jan 9:rs.3.rs-2382345. doi: 10.21203/rs.3.rs-2382345/v1. Res Sq. 2023. PMID: 36711785 Free PMC article. Updated. Preprint.
Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans.
Asiimwe R, Knott B, Greene ME, Wright E, Bell M, Epstein D, Yates SD, Cheung MD, Gonzalez MV, Fry S, Boydston E, Clevenger S, Locke JE, George JF, Burney R, Arora N, Duncan VE, Richter HE, Gunn D, Freud AG, Little SC, Porrett PM. Asiimwe R, et al. Among authors: cheung md. bioRxiv [Preprint]. 2024 Mar 12:2024.03.07.583906. doi: 10.1101/2024.03.07.583906. bioRxiv. 2024. PMID: 38559147 Free PMC article. Preprint.
Spatiotemporal immune atlas of a clinical-grade gene-edited pig-to-human kidney xenotransplant.
Cheung MD, Asiimwe R, Erman EN, Fucile CF, Liu S, Sun CW, Hanumanthu VS, Pal HC, Wright ED, Ghajar-Rahimi G, Epstein D, Orandi BJ, Kumar V, Anderson DJ, Greene ME, Bell M, Yates S, Moore KH, LaFontaine J, Killian JT Jr, Baker G, Perry J, Khan Z, Reed R, Little SC, Rosenberg AF, George JF, Locke JE, Porrett PM. Cheung MD, et al. Nat Commun. 2024 Apr 11;15(1):3140. doi: 10.1038/s41467-024-47454-7. Nat Commun. 2024. PMID: 38605083 Free PMC article.
Nicotinamide Adenine Dinucleotide Biosynthetic Impairment and Urinary Metabolomic Alterations Observed in Hospitalized Adults With COVID-19-Related Acute Kidney Injury.
Raines NH, Cheung MD, Wilson LS, Edberg JC, Erdmann NB, Schmaier AA, Berryhill TF, Manickas-Hill Z, Li JZ, Yu XG, Agarwal A, Barnes S, Parikh SM. Raines NH, et al. Among authors: cheung md. Kidney Int Rep. 2021 Dec;6(12):3002-3013. doi: 10.1016/j.ekir.2021.09.001. Epub 2021 Sep 14. Kidney Int Rep. 2021. PMID: 34541422 Free PMC article.