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Cancer vaccines based on whole-tumor lysate or neoepitopes with validated HLA binding outperform those with predicted HLA-binding affinity.
Fritah H, Graciotti M, Lai-Lai Chiang C, Huguenin-Bergenat AL, Petremand R, Ahmed R, Guillaume P, Schmidt J, Stevenson BJ, Gfeller D, Harari A, Kandalaft LE. Fritah H, et al. Among authors: lai lai chiang c. iScience. 2023 Feb 27;26(4):106288. doi: 10.1016/j.isci.2023.106288. eCollection 2023 Apr 21. iScience. 2023. PMID: 36950115 Free PMC article.
The current clinical landscape of personalized cancer vaccines.
Fritah H, Rovelli R, Chiang CL, Kandalaft LE. Fritah H, et al. Among authors: chiang cl. Cancer Treat Rev. 2022 May;106:102383. doi: 10.1016/j.ctrv.2022.102383. Epub 2022 Mar 24. Cancer Treat Rev. 2022. PMID: 35367804 Free article. Review.
Whole Tumor Antigen Vaccines: Where Are We?
Chiang CL, Coukos G, Kandalaft LE. Chiang CL, et al. Vaccines (Basel). 2015 Apr 23;3(2):344-72. doi: 10.3390/vaccines3020344. Vaccines (Basel). 2015. PMID: 26343191 Free PMC article. Review.
A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside.
Chiang CL, Kandalaft LE, Tanyi J, Hagemann AR, Motz GT, Svoronos N, Montone K, Mantia-Smaldone GM, Smith L, Nisenbaum HL, Levine BL, Kalos M, Czerniecki BJ, Torigian DA, Powell DJ Jr, Mick R, Coukos G. Chiang CL, et al. Clin Cancer Res. 2013 Sep 1;19(17):4801-15. doi: 10.1158/1078-0432.CCR-13-1185. Epub 2013 Jul 9. Clin Cancer Res. 2013. PMID: 23838316 Free PMC article.
13 results