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Regulation of mammalian Ste20 (Mst) kinases.
Rawat SJ, Chernoff J. Rawat SJ, et al. Among authors: chernoff j. Trends Biochem Sci. 2015 Mar;40(3):149-56. doi: 10.1016/j.tibs.2015.01.001. Epub 2015 Feb 6. Trends Biochem Sci. 2015. PMID: 25665457 Free PMC article. Review.
H-ras Inhibits the Hippo Pathway by Promoting Mst1/Mst2 Heterodimerization.
Rawat SJ, Araiza-Olivera D, Arias-Romero LE, Villamar-Cruz O, Prudnikova TY, Roder H, Chernoff J. Rawat SJ, et al. Among authors: chernoff j. Curr Biol. 2016 Jun 20;26(12):1556-1563. doi: 10.1016/j.cub.2016.04.027. Epub 2016 May 26. Curr Biol. 2016. PMID: 27238285 Free PMC article.
Hras helps hippo heterodimerize to evade tumor suppression.
Araiza-Olivera D, Chernoff J. Araiza-Olivera D, et al. Among authors: chernoff j. Small GTPases. 2018 Jul 4;9(4):327-331. doi: 10.1080/21541248.2016.1228794. Epub 2016 Sep 20. Small GTPases. 2018. PMID: 27560370 Free PMC article. Review.
Targeting PAK1.
Semenova G, Chernoff J. Semenova G, et al. Among authors: chernoff j. Biochem Soc Trans. 2017 Feb 8;45(1):79-88. doi: 10.1042/BST20160134. Biochem Soc Trans. 2017. PMID: 28202661 Free PMC article. Review.
A New Rho(d) Map to Diffuse Gastric Cancer.
Benton D, Chernoff J. Benton D, et al. Among authors: chernoff j. Cancer Discov. 2020 Feb;10(2):182-184. doi: 10.1158/2159-8290.CD-19-1327. Cancer Discov. 2020. PMID: 32024682 Free PMC article.
PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
Hawley E, Gehlhausen J, Karchugina S, Chow HY, Araiza-Olivera D, Radu M, Smith A, Burks C, Jiang L, Li X, Bessler W, Masters A, Edwards D, Burgin C, Jones D, Yates C, Clapp DW, Chernoff J, Park SJ. Hawley E, et al. Among authors: chernoff j. Hum Mol Genet. 2021 Aug 12;30(17):1607-1617. doi: 10.1093/hmg/ddab106. Hum Mol Genet. 2021. PMID: 34075397 Free PMC article.
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling.
Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR. Sementino E, et al. Among authors: chernoff j. Mol Cancer Res. 2022 May 4;20(5):699-711. doi: 10.1158/1541-7786.MCR-21-0837. Mol Cancer Res. 2022. PMID: 35082167 Free PMC article.
223 results