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Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation.
Mousset A, Lecorgne E, Bourget I, Lopez P, Jenovai K, Cherfils-Vicini J, Dominici C, Rios G, Girard-Riboulleau C, Liu B, Spector DL, Ehmsen S, Renault S, Hego C, Mechta-Grigoriou F, Bidard FC, Terp MG, Egeblad M, Gaggioli C, Albrengues J. Mousset A, et al. Among authors: cherfils vicini j. Cancer Cell. 2023 Apr 10;41(4):757-775.e10. doi: 10.1016/j.ccell.2023.03.008. Cancer Cell. 2023. PMID: 37037615 Free PMC article.
Tumor microenvironment is multifaceted.
Sautès-Fridman C, Cherfils-Vicini J, Damotte D, Fisson S, Fridman WH, Cremer I, Dieu-Nosjean MC. Sautès-Fridman C, et al. Cancer Metastasis Rev. 2011 Mar;30(1):13-25. doi: 10.1007/s10555-011-9279-y. Cancer Metastasis Rev. 2011. PMID: 21271351 Review.
TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.
Benarroch-Popivker D, Pisano S, Mendez-Bermudez A, Lototska L, Kaur P, Bauwens S, Djerbi N, Latrick CM, Fraisier V, Pei B, Gay A, Jaune E, Foucher K, Cherfils-Vicini J, Aeby E, Miron S, Londoño-Vallejo A, Ye J, Le Du MH, Wang H, Gilson E, Giraud-Panis MJ. Benarroch-Popivker D, et al. Mol Cell. 2016 Jan 21;61(2):274-86. doi: 10.1016/j.molcel.2015.12.009. Epub 2016 Jan 7. Mol Cell. 2016. PMID: 26774283 Free PMC article.
Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2.
Cherfils-Vicini J, Iltis C, Cervera L, Pisano S, Croce O, Sadouni N, Győrffy B, Collet R, Renault VM, Rey-Millet M, Leonetti C, Zizza P, Allain F, Ghiringhelli F, Soubeiran N, Shkreli M, Vivier E, Biroccio A, Gilson E. Cherfils-Vicini J, et al. EMBO J. 2019 Jun 3;38(11):e100012. doi: 10.15252/embj.2018100012. Epub 2019 Apr 18. EMBO J. 2019. PMID: 31000523 Free PMC article.
A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy.
Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, Duranton C, Ryffel B, Kanellopoulos J, Delarasse C, Renault N, Furman C, Homerin G, Féral C, Cherfils-Vicini J, Millet R, Adriouch S, Ghinet A, Hofman P, Vouret-Craviari V. Douguet L, et al. Among authors: cherfils vicini j. Nat Commun. 2021 Jan 28;12(1):653. doi: 10.1038/s41467-021-20912-2. Nat Commun. 2021. PMID: 33510147 Free PMC article.
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