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Endothelial OCT4 is atheroprotective by preventing metabolic and phenotypic dysfunction.
Shin J, Tkachenko S, Chaklader M, Pletz C, Singh K, Bulut GB, Han YM, Mitchell K, Baylis RA, Kuzmin AA, Hu B, Lathia JD, Stenina-Adognravi O, Podrez E, Byzova TV, Owens GK, Cherepanova OA. Shin J, et al. Among authors: cherepanova oa. Cardiovasc Res. 2022 Aug 24;118(11):2458-2477. doi: 10.1093/cvr/cvac036. Cardiovasc Res. 2022. PMID: 35325071 Free PMC article.
Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective.
Cherepanova OA, Gomez D, Shankman LS, Swiatlowska P, Williams J, Sarmento OF, Alencar GF, Hess DL, Bevard MH, Greene ES, Murgai M, Turner SD, Geng YJ, Bekiranov S, Connelly JJ, Tomilin A, Owens GK. Cherepanova OA, et al. Nat Med. 2016 Jun;22(6):657-65. doi: 10.1038/nm.4109. Epub 2016 May 16. Nat Med. 2016. PMID: 27183216 Free PMC article.
Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions.
Durgin BG, Cherepanova OA, Gomez D, Karaoli T, Alencar GF, Butcher JT, Zhou YQ, Bendeck MP, Isakson BE, Owens GK, Connelly JJ. Durgin BG, et al. Among authors: cherepanova oa. Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H943-H958. doi: 10.1152/ajpheart.00029.2017. Epub 2017 Mar 10. Am J Physiol Heart Circ Physiol. 2017. PMID: 28283548 Free PMC article.
34 results