Cheng L - Search Results

1

Hepatic mitochondrial NAD + transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis.

Cheng L, Deepak RNVK, Wang G, Meng Z, Tao L, Xie M, Chi W, Zhang Y, Yang M, Liao Y, Chen R, Liang Y, Zhang J, Huang Y, Wang W, Guo Z, Wang Y, Lin JD, Fan H, Chen L. Cheng L, et al. Hepatology. 2023 Dec 1;78(6):1828-1842. doi: 10.1097/HEP.0000000000000314. Epub 2023 Feb 22. Hepatology. 2023. PMID: 36804859 Free PMC article.

2

Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening.

Ung PM, Song W, Cheng L, Zhao X, Hu H, Chen L, Schlessinger A. Ung PM, et al. Among authors: cheng l. ACS Chem Biol. 2016 Jul 15;11(7):1908-16. doi: 10.1021/acschembio.6b00304. Epub 2016 May 11. ACS Chem Biol. 2016. PMID: 27128978 Free PMC article.

3

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.

Liu P, Ge M, Hu J, Li X, Che L, Sun K, Cheng L, Huang Y, Pilo MG, Cigliano A, Pes GM, Pascale RM, Brozzetti S, Vidili G, Porcu A, Cossu A, Palmieri G, Sini MC, Ribback S, Dombrowski F, Tao J, Calvisi DF, Chen L, Chen X. Liu P, et al. Among authors: cheng l. Hepatology. 2017 Jul;66(1):167-181. doi: 10.1002/hep.29183. Epub 2017 May 22. Hepatology. 2017. PMID: 28370287 Free PMC article.

4

Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.

Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, Chen J, Huo Y, Xu L, Liu X, Deng H, Siegenthaler JA, Chen L. Zhao X, et al. Among authors: cheng l. Sci Rep. 2017 Apr 11;7:46344. doi: 10.1038/srep46344. Sci Rep. 2017. PMID: 28397817 Free PMC article.

5

Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.

Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Cheng L, et al. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-017-2048-0. Epub 2017 Sep 4. Arch Toxicol. 2018. PMID: 28871336 Free PMC article.

6

Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.

Song W, Luo Q, Zhang Y, Zhou L, Liu Y, Ma Z, Guo J, Huang Y, Cheng L, Meng Z, Li Z, Zhang B, Li S, Yee SW, Fan H, Li P, Giacomini KM, Chen L. Song W, et al. Among authors: cheng l. PLoS Biol. 2019 Jan 17;17(1):e2006571. doi: 10.1371/journal.pbio.2006571. eCollection 2019 Jan. PLoS Biol. 2019. PMID: 30653498 Free PMC article.

7

SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility.

Kuang W, Zhang J, Lan Z, Deepak RNVK, Liu C, Ma Z, Cheng L, Zhao X, Meng X, Wang W, Wang X, Xu L, Jiao Y, Luo Q, Meng Z, Kee K, Liu X, Deng H, Li W, Fan H, Chen L. Kuang W, et al. Among authors: cheng l. Cell Rep. 2021 Apr 20;35(3):109025. doi: 10.1016/j.celrep.2021.109025. Cell Rep. 2021. PMID: 33882315 Free PMC article.

8

Ablation of Proton/Glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis.

Liu Y, Chi W, Tao L, Wang G, Deepak RNVK, Sheng L, Chen T, Feng Y, Cao X, Cheng L, Zhao X, Liu X, Deng H, Fan H, Jiang P, Chen L. Liu Y, et al. Among authors: cheng l. J Invest Dermatol. 2022 Oct;142(10):2744-2755.e9. doi: 10.1016/j.jid.2022.04.008. Epub 2022 Apr 23. J Invest Dermatol. 2022. PMID: 35469906 Free article.

9

MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.

Chi W, Kang N, Sheng L, Liu S, Tao L, Cao X, Liu Y, Zhu C, Zhang Y, Wu B, Chen R, Cheng L, Wang J, Sun X, Liu X, Deng H, Yang J, Li Z, Liu W, Chen L. Chi W, et al. Among authors: cheng l. Nat Commun. 2024 Jan 2;15(1):163. doi: 10.1038/s41467-023-44540-0. Nat Commun. 2024. PMID: 38167945 Free PMC article.

10

Structural insights into human organic cation transporter 1 transport and inhibition.

Zhang S, Zhu A, Kong F, Chen J, Lan B, He G, Gao K, Cheng L, Sun X, Yan C, Chen L, Liu X. Zhang S, et al. Among authors: cheng l. Cell Discov. 2024 Mar 15;10(1):30. doi: 10.1038/s41421-024-00664-1. Cell Discov. 2024. PMID: 38485705 Free PMC article.

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