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Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma.
Kirschenbaum D, Xie K, Ingelfinger F, Katzenelenbogen Y, Abadie K, Look T, Sheban F, Phan TS, Li B, Zwicky P, Yofe I, David E, Mazuz K, Hou J, Chen Y, Shaim H, Shanley M, Becker S, Qian J, Colonna M, Ginhoux F, Rezvani K, Theis FJ, Yosef N, Weiss T, Weiner A, Amit I. Kirschenbaum D, et al. Among authors: chen y. Cell. 2024 Jan 4;187(1):149-165.e23. doi: 10.1016/j.cell.2023.11.032. Epub 2023 Dec 21. Cell. 2024. PMID: 38134933
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Molgora M, Esaulova E, Vermi W, Hou J, Chen Y, Luo J, Brioschi S, Bugatti M, Omodei AS, Ricci B, Fronick C, Panda SK, Takeuchi Y, Gubin MM, Faccio R, Cella M, Gilfillan S, Unanue ER, Artyomov MN, Schreiber RD, Colonna M. Molgora M, et al. Among authors: chen y. Cell. 2020 Aug 20;182(4):886-900.e17. doi: 10.1016/j.cell.2020.07.013. Epub 2020 Aug 11. Cell. 2020. PMID: 32783918 Free PMC article.
Activated microglia mitigate Aβ-associated tau seeding and spreading.
Gratuze M, Chen Y, Parhizkar S, Jain N, Strickland MR, Serrano JR, Colonna M, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: chen y. J Exp Med. 2021 Aug 2;218(8):e20210542. doi: 10.1084/jem.20210542. Epub 2021 Jun 8. J Exp Med. 2021. PMID: 34100905 Free PMC article.
TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Wang S, Sudan R, Peng V, Zhou Y, Du S, Yuede CM, Lei T, Hou J, Cai Z, Cella M, Nguyen K, Poliani PL, Beatty WL, Chen Y, Cao S, Lin K, Rodrigues C, Ellebedy AH, Gilfillan S, Brown GD, Holtzman DM, Brioschi S, Colonna M. Wang S, et al. Among authors: chen y. Cell. 2022 Oct 27;185(22):4153-4169.e19. doi: 10.1016/j.cell.2022.09.033. Cell. 2022. PMID: 36306735 Free PMC article.
Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination.
Hou J, Zhou Y, Cai Z, Terekhova M, Swain A, Andhey PS, Guimaraes RM, Ulezko Antonova A, Qiu T, Sviben S, Strout G, Fitzpatrick JAJ, Chen Y, Gilfillan S, Kim DH, Van Dyken SJ, Artyomov MN, Colonna M. Hou J, et al. Among authors: chen y. Cell Rep. 2023 Apr 25;42(4):112293. doi: 10.1016/j.celrep.2023.112293. Epub 2023 Mar 21. Cell Rep. 2023. PMID: 36952346 Free PMC article.
165,162 results
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