Chen Y - Search Results

1

Enhancer reprogramming promotes the activation of cancer-associated fibroblasts and breast cancer metastasis.

Li Q, Lv X, Han C, Kong Y, Dai Z, Huo D, Li T, Li D, Li W, Wang X, Zhao Q, Ming J, Yang W, Chen Y, Wu X. Li Q, et al. Among authors: chen y. Theranostics. 2022 Oct 24;12(17):7491-7508. doi: 10.7150/thno.75853. eCollection 2022. Theranostics. 2022. PMID: 36438487 Free PMC article.

2

Clinical and therapeutic relevance of cancer-associated fibroblasts.

Chen Y, McAndrews KM, Kalluri R. Chen Y, et al. Nat Rev Clin Oncol. 2021 Dec;18(12):792-804. doi: 10.1038/s41571-021-00546-5. Epub 2021 Sep 6. Nat Rev Clin Oncol. 2021. PMID: 34489603 Free PMC article. Review.

3

Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.

McAndrews KM, Chen Y, Darpolor JK, Zheng X, Yang S, Carstens JL, Li B, Wang H, Miyake T, Correa de Sampaio P, Kirtley ML, Natale M, Wu CC, Sugimoto H, LeBleu VS, Kalluri R. McAndrews KM, et al. Among authors: chen y. Cancer Discov. 2022 Jun 2;12(6):1580-1597. doi: 10.1158/2159-8290.CD-20-1484. Cancer Discov. 2022. PMID: 35348629 Free PMC article.

4

Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis.

Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Chen Y, et al. PLoS Biol. 2018 Dec 28;16(12):e2005907. doi: 10.1371/journal.pbio.2005907. eCollection 2018 Dec. PLoS Biol. 2018. PMID: 30592710 Free PMC article.

5

Type I collagen deletion in αSMA⁺ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer.

Chen Y, Kim J, Yang S, Wang H, Wu CJ, Sugimoto H, LeBleu VS, Kalluri R. Chen Y, et al. Cancer Cell. 2021 Apr 12;39(4):548-565.e6. doi: 10.1016/j.ccell.2021.02.007. Epub 2021 Mar 4. Cancer Cell. 2021. PMID: 33667385 Free PMC article.

6

Cross-Dataset Single-Cell Analysis Identifies Temporal Alterations in Cell Populations of Primary Pancreatic Tumor and Liver Metastasis.

Yang D, Moniruzzaman R, Wang H, Wang H, Chen Y. Yang D, et al. Among authors: chen y. Cancers (Basel). 2023 Apr 21;15(8):2396. doi: 10.3390/cancers15082396. Cancers (Basel). 2023. PMID: 37190324 Free PMC article.

7

Single-Cell Analysis Differentiates the Effects of p53 Mutation and p53 Loss on Cell Compositions of Oncogenic Kras-Driven Pancreatic Cancer.

Sun X, Yang D, Chen Y. Sun X, et al. Among authors: chen y. Cells. 2023 Nov 12;12(22):2614. doi: 10.3390/cells12222614. Cells. 2023. PMID: 37998349 Free PMC article.

8

Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.

Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Saur D, Kalluri R. Chen Y, et al. EMBO Mol Med. 2018 Oct;10(10):e9085. doi: 10.15252/emmm.201809085. EMBO Mol Med. 2018. PMID: 30120146 Free PMC article.

9

Stromal Cells Exhibit Prevalent Genetic Aberrations in Colorectal Cancer.

McAndrews KM, Chen Y, Kalluri R. McAndrews KM, et al. Among authors: chen y. Cancer Cell. 2020 Dec 14;38(6):774-775. doi: 10.1016/j.ccell.2020.11.003. Cancer Cell. 2020. PMID: 33321084 Free article.

10

Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8⁺ T cells.

Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, McAndrews KM, Kalluri R. Mahadevan KK, et al. Among authors: chen y. Dev Cell. 2023 Sep 11;58(17):1562-1577.e8. doi: 10.1016/j.devcel.2023.07.025. Epub 2023 Aug 24. Dev Cell. 2023. PMID: 37625403

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