Chen Y - Search Results

1

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.

Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. Hou J, et al. Among authors: chen y. Nat Cell Biol. 2020 Oct;22(10):1264-1275. doi: 10.1038/s41556-020-0575-z. Epub 2020 Sep 14. Nat Cell Biol. 2020. PMID: 32929201 Free PMC article.

2

Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug.

Wang YC, Yang WH, Yang CS, Hou MH, Tsai CL, Chou YZ, Hung MC, Chen Y. Wang YC, et al. Among authors: chen y. Am J Cancer Res. 2020 Aug 1;10(8):2535-2545. eCollection 2020. Am J Cancer Res. 2020. PMID: 32905393 Free PMC article.

3

Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma.

Liu C, Zha Z, Zhou C, Chen Y, Xia W, Wang YN, Lee HH, Yin Y, Yan M, Chang CW, Chan LC, Qiu Y, Li H, Li CW, Hsu JM, Hsu JL, Wang SC, Ren N, Hung MC. Liu C, et al. Among authors: chen y. J Hepatol. 2021 Apr;74(4):907-918. doi: 10.1016/j.jhep.2020.09.030. Epub 2020 Oct 5. J Hepatol. 2021. PMID: 33031845 Free PMC article.

4

Author Correction: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.

Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. Hou J, et al. Among authors: chen y. Nat Cell Biol. 2020 Nov;22(11):1396. doi: 10.1038/s41556-020-00599-1. Nat Cell Biol. 2020. PMID: 33033376

5

Cigarette smoke-induced LKB1/AMPK pathway deficiency reduces EGFR TKI sensitivity in NSCLC.

Cheng FJ, Chen CH, Tsai WC, Wang BW, Yu MC, Hsia TC, Wei YL, Hsiao YC, Hu DW, Ho CY, Li TS, Wu CY, Chou WY, Yu YL, Tang CH, Chen CY, Chen CM, Hsu JL, Chen HF, Chen Y, Tu CY, Hung MC, Huang WC. Cheng FJ, et al. Among authors: chen hf, chen ch, chen cy, chen cm, chen y. Oncogene. 2021 Feb;40(6):1162-1175. doi: 10.1038/s41388-020-01597-1. Epub 2020 Dec 17. Oncogene. 2021. PMID: 33335306 Free PMC article.

6

Crystal structure of the N-terminal domain of TagH reveals a potential drug targeting site.

Yang CS, Huang WC, Ko TP, Wang YC, Wang AH, Chen Y. Yang CS, et al. Among authors: chen y. Biochem Biophys Res Commun. 2021 Jan 15;536:1-6. doi: 10.1016/j.bbrc.2020.12.028. Epub 2020 Dec 22. Biochem Biophys Res Commun. 2021. PMID: 33360015

7

Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease.

Wang SC, Chen Y, Wang YC, Wang WJ, Yang CS, Tsai CL, Hou MH, Chen HF, Shen YC, Hung MC. Wang SC, et al. Among authors: chen hf, chen y. Am J Cancer Res. 2020 Dec 1;10(12):4538-4546. eCollection 2020. Am J Cancer Res. 2020. PMID: 33415017 Free PMC article.

8

Screening strategy of TMPRSS2 inhibitors by FRET-based enzymatic activity for TMPRSS2-based cancer and COVID-19 treatment.

Chen Y, Huang WC, Yang CS, Cheng FJ, Chiu YF, Chen HF, Huynh TK, Huang CF, Chen CH, Wang HC, Hung MC. Chen Y, et al. Among authors: chen hf, chen ch. Am J Cancer Res. 2021 Mar 1;11(3):827-836. eCollection 2021. Am J Cancer Res. 2021. PMID: 33791156 Free PMC article.

9

Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.

Ko TP, Wang YC, Tsai CL, Yang CS, Hou MH, Chen Y. Ko TP, et al. Among authors: chen y. Nucleic Acids Res. 2021 May 7;49(8):4725-4737. doi: 10.1093/nar/gkab165. Nucleic Acids Res. 2021. PMID: 33836064 Free PMC article.

10

Scutellaria barbata D. Don Inhibits the Main Proteases (M^pro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection.

Huang ST, Chen Y, Chang WC, Chen HF, Lai HC, Lin YC, Wang WJ, Wang YC, Yang CS, Wang SC, Hung MC. Huang ST, et al. Among authors: chen hf, chen y. Viruses. 2021 May 2;13(5):826. doi: 10.3390/v13050826. Viruses. 2021. PMID: 34063247 Free PMC article.

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