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Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing.
Alkner S, Tang MH, Brueffer C, Dahlgren M, Chen Y, Olsson E, Winter C, Baker S, Ehinger A, Rydén L, Saal LH, Fernö M, Gruvberger-Saal SK. Alkner S, et al. Among authors: chen y. Breast Cancer Res. 2015 Aug 5;17(1):102. doi: 10.1186/s13058-015-0608-x. Breast Cancer Res. 2015. PMID: 26242876 Free PMC article.
Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease.
Olsson E, Winter C, George A, Chen Y, Howlin J, Tang MH, Dahlgren M, Schulz R, Grabau D, van Westen D, Fernö M, Ingvar C, Rose C, Bendahl PO, Rydén L, Borg Å, Gruvberger-Saal SK, Jernström H, Saal LH. Olsson E, et al. Among authors: chen y. EMBO Mol Med. 2015 Aug;7(8):1034-47. doi: 10.15252/emmm.201404913. EMBO Mol Med. 2015. PMID: 25987569 Free PMC article.
PTEN and NEDD4 in Human Breast Carcinoma.
Chen Y, van de Vijver MJ, Hibshoosh H, Parsons R, Saal LH. Chen Y, et al. Pathol Oncol Res. 2016 Jan;22(1):41-7. doi: 10.1007/s12253-015-9971-2. Epub 2015 Aug 15. Pathol Oncol Res. 2016. PMID: 26276352 Free PMC article.
Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencing.
Tang MH, Dahlgren M, Brueffer C, Tjitrowirjo T, Winter C, Chen Y, Olsson E, Wang K, Törngren T, Sjöström M, Grabau D, Bendahl PO, Rydén L, Niméus E, Saal LH, Borg Å, Gruvberger-Saal SK. Tang MH, et al. Among authors: chen y. Oncotarget. 2015 Nov 10;6(35):37169-84. doi: 10.18632/oncotarget.5951. Oncotarget. 2015. PMID: 26439695 Free PMC article.
Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, Saal LH. She QB, et al. Among authors: chen y. BMC Cancer. 2016 Aug 2;16:587. doi: 10.1186/s12885-016-2609-2. BMC Cancer. 2016. PMID: 27484095 Free PMC article.
Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment.
Förnvik D, Aaltonen KE, Chen Y, George AM, Brueffer C, Rigo R, Loman N, Saal LH, Rydén L. Förnvik D, et al. Among authors: chen y. Breast Cancer Res Treat. 2019 Sep;177(2):447-455. doi: 10.1007/s10549-019-05326-5. Epub 2019 Jun 24. Breast Cancer Res Treat. 2019. PMID: 31236809 Free PMC article.
Clinical Value of RNA Sequencing-Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network-Breast Initiative.
Brueffer C, Vallon-Christersson J, Grabau D, Ehinger A, Häkkinen J, Hegardt C, Malina J, Chen Y, Bendahl PO, Manjer J, Malmberg M, Larsson C, Loman N, Rydén L, Borg Å, Saal LH. Brueffer C, et al. Among authors: chen y. JCO Precis Oncol. 2018 Mar 9;2:PO.17.00135. doi: 10.1200/PO.17.00135. eCollection 2018. JCO Precis Oncol. 2018. PMID: 32913985 Free PMC article.
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