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Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis.
Fong MY, Zhou W, Liu L, Alontaga AY, Chandra M, Ashby J, Chow A, O'Connor ST, Li S, Chin AR, Somlo G, Palomares M, Li Z, Tremblay JR, Tsuyada A, Sun G, Reid MA, Wu X, Swiderski P, Ren X, Shi Y, Kong M, Zhong W, Chen Y, Wang SE. Fong MY, et al. Among authors: chen y. Nat Cell Biol. 2015 Feb;17(2):183-94. doi: 10.1038/ncb3094. Epub 2015 Jan 26. Nat Cell Biol. 2015. PMID: 25621950 Free PMC article.
Biochemical analysis of protein SUMOylation.
Alontaga AY, Bobkova E, Chen Y. Alontaga AY, et al. Among authors: chen y. Curr Protoc Mol Biol. 2012 Jul;Chapter 10:Unit10.29. doi: 10.1002/0471142727.mb1029s99. Curr Protoc Mol Biol. 2012. PMID: 22870855 Free PMC article.
Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface.
Alontaga AY, Li Y, Chen CH, Ma CT, Malany S, Key DE, Sergienko E, Sun Q, Whipple DA, Matharu DS, Li B, Vega R, Li YJ, Schoenen FJ, Blagg BS, Chung TD, Chen Y. Alontaga AY, et al. Among authors: chen ch, chen y. ACS Comb Sci. 2015 Apr 13;17(4):239-46. doi: 10.1021/co500181b. Epub 2015 Mar 23. ACS Comb Sci. 2015. PMID: 25719760 Free PMC article.
RWD Domain as an E2 (Ubc9)-Interaction Module.
Alontaga AY, Ambaye ND, Li YJ, Vega R, Chen CH, Bzymek KP, Williams JC, Hu W, Chen Y. Alontaga AY, et al. Among authors: chen ch, chen y. J Biol Chem. 2015 Jul 3;290(27):16550-9. doi: 10.1074/jbc.M115.644047. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918163 Free PMC article.
Reply to Function and Structure of the RWD Domain.
Alontaga A, Chen Y. Alontaga A, et al. Among authors: chen y. J Biol Chem. 2015 Aug 14;290(33):20628. doi: 10.1074/jbc.l115.677229. J Biol Chem. 2015. PMID: 26495453 Free PMC article. No abstract available.
Observation of an E2 (Ubc9)-homodimer by crystallography.
Alontaga AY, Ambaye ND, Li YJ, Vega R, Chen CH, Bzymek KP, Williams JC, Hu W, Chen Y. Alontaga AY, et al. Among authors: chen ch, chen y. Data Brief. 2016 Feb 12;7:195-200. doi: 10.1016/j.dib.2016.02.015. eCollection 2016 Jun. Data Brief. 2016. PMID: 27408909 Free PMC article.
Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells.
Yan W, Wu X, Zhou W, Fong MY, Cao M, Liu J, Liu X, Chen CH, Fadare O, Pizzo DP, Wu J, Liu L, Liu X, Chin AR, Ren X, Chen Y, Locasale JW, Wang SE. Yan W, et al. Among authors: chen ch, chen y. Nat Cell Biol. 2018 May;20(5):597-609. doi: 10.1038/s41556-018-0083-6. Epub 2018 Apr 16. Nat Cell Biol. 2018. PMID: 29662176 Free PMC article.
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