Chen X - Search Results

1

Functional interrogation of DNA damage response variants with base editing screens.

Cuella-Martin R, Hayward SB, Fan X, Chen X, Huang JW, Taglialatela A, Leuzzi G, Zhao J, Rabadan R, Lu C, Shen Y, Ciccia A. Cuella-Martin R, et al. Among authors: chen x. Cell. 2021 Feb 18;184(4):1081-1097.e19. doi: 10.1016/j.cell.2021.01.041. Cell. 2021. PMID: 33606978 Free PMC article.

2

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.

Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, Keogh MC, Bareke E, Djedid A, Harutyunyan AS, Jabado N, Garcia BA, Li H, Allis CD, Majewski J, Lu C. Weinberg DN, et al. Among authors: chen h, chen x. Nature. 2019 Sep;573(7773):281-286. doi: 10.1038/s41586-019-1534-3. Epub 2019 Sep 4. Nature. 2019. PMID: 31485078 Free PMC article.

3

Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells.

Liu C, Tate T, Batourina E, Truschel ST, Potter S, Adam M, Xiang T, Picard M, Reiley M, Schneider K, Tamargo M, Lu C, Chen X, He J, Kim H, Mendelsohn CL. Liu C, et al. Among authors: chen x. Nat Commun. 2019 Oct 9;10(1):4589. doi: 10.1038/s41467-019-12332-0. Nat Commun. 2019. PMID: 31597917 Free PMC article.

4

The INO80 Complex Regulates Epigenetic Inheritance of Heterochromatin.

Shan CM, Bao K, Diedrich J, Chen X, Lu C, Yates JR 3rd, Jia S. Shan CM, et al. Among authors: chen x. Cell Rep. 2020 Dec 29;33(13):108561. doi: 10.1016/j.celrep.2020.108561. Cell Rep. 2020. PMID: 33378674 Free PMC article.

5

Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.

Rajagopalan KN, Chen X, Weinberg DN, Chen H, Majewski J, Allis CD, Lu C. Rajagopalan KN, et al. Among authors: chen x, chen h. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2021795118. doi: 10.1073/pnas.2021795118. Proc Natl Acad Sci U S A. 2021. PMID: 33619101 Free PMC article.

6

Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma.

Farhangdoost N, Horth C, Hu B, Bareke E, Chen X, Li Y, Coradin M, Garcia BA, Lu C, Majewski J. Farhangdoost N, et al. Among authors: chen x. Cell Rep. 2021 Feb 23;34(8):108769. doi: 10.1016/j.celrep.2021.108769. Cell Rep. 2021. PMID: 33626351 Free PMC article.

7

The interplay between DNA and histone methylation: molecular mechanisms and disease implications.

Li Y, Chen X, Lu C. Li Y, et al. Among authors: chen x. EMBO Rep. 2021 May 5;22(5):e51803. doi: 10.15252/embr.202051803. Epub 2021 Apr 12. EMBO Rep. 2021. PMID: 33844406 Free PMC article. Review.

8

Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.

Weinberg DN, Rosenbaum P, Chen X, Barrows D, Horth C, Marunde MR, Popova IK, Gillespie ZB, Keogh MC, Lu C, Majewski J, Allis CD. Weinberg DN, et al. Among authors: chen x. Nat Genet. 2021 Jun;53(6):794-800. doi: 10.1038/s41588-021-00856-5. Epub 2021 May 13. Nat Genet. 2021. PMID: 33986537 Free PMC article.

9

Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors.

Sheikh TN, Chen X, Xu X, McGuire JT, Ingham M, Lu C, Schwartz GK. Sheikh TN, et al. Among authors: chen x. Mol Cancer Ther. 2021 Dec;20(12):2362-2371. doi: 10.1158/1535-7163.MCT-21-0066. Epub 2021 Sep 22. Mol Cancer Ther. 2021. PMID: 34552007 Free PMC article.

10

Pparg signaling controls bladder cancer subtype and immune exclusion.

Tate T, Xiang T, Wobker SE, Zhou M, Chen X, Kim H, Batourina E, Lin CS, Kim WY, Lu C, Mckiernan JM, Mendelsohn CL. Tate T, et al. Among authors: chen x. Nat Commun. 2021 Oct 25;12(1):6160. doi: 10.1038/s41467-021-26421-6. Nat Commun. 2021. PMID: 34697317 Free PMC article.

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