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Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs.
Osborn MJ, Newby GA, McElroy AN, Knipping F, Nielsen SC, Riddle MJ, Xia L, Chen W, Eide CR, Webber BR, Wandall HH, Dabelsteen S, Blazar BR, Liu DR, Tolar J. Osborn MJ, et al. Among authors: chen w. J Invest Dermatol. 2020 Feb;140(2):338-347.e5. doi: 10.1016/j.jid.2019.07.701. Epub 2019 Aug 19. J Invest Dermatol. 2020. PMID: 31437443 Free PMC article.
Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium.
Lindborg BA, Brekke JH, Vegoe AL, Ulrich CB, Haider KT, Subramaniam S, Venhuizen SL, Eide CR, Orchard PJ, Chen W, Wang Q, Pelaez F, Scott CM, Kokkoli E, Keirstead SA, Dutton JR, Tolar J, O'Brien TD. Lindborg BA, et al. Among authors: chen w. Stem Cells Transl Med. 2016 Jul;5(7):970-9. doi: 10.5966/sctm.2015-0305. Epub 2016 May 13. Stem Cells Transl Med. 2016. PMID: 27177577 Free PMC article.
Rapid DNA replication origin licensing protects stem cell pluripotency.
Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, Cook JG. Matson JP, et al. Among authors: chen w. Elife. 2017 Nov 17;6:e30473. doi: 10.7554/eLife.30473. Elife. 2017. PMID: 29148972 Free PMC article.
ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. Rousseaux MWC, et al. Among authors: chen w. Neuron. 2018 Mar 21;97(6):1235-1243.e5. doi: 10.1016/j.neuron.2018.02.013. Epub 2018 Mar 8. Neuron. 2018. PMID: 29526553 Free PMC article.
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