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Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.
Dogruluk T, Tsang YH, Espitia M, Chen F, Chen T, Chong Z, Appadurai V, Dogruluk A, Eterovic AK, Bonnen PE, Creighton CJ, Chen K, Mills GB, Scott KL. Dogruluk T, et al. Among authors: chen k, chen t, chen f. Cancer Res. 2015 Dec 15;75(24):5341-54. doi: 10.1158/0008-5472.CAN-15-1654. Epub 2015 Dec 1. Cancer Res. 2015. PMID: 26627007 Free PMC article.
Bias from removing read duplication in ultra-deep sequencing experiments.
Zhou W, Chen T, Zhao H, Eterovic AK, Meric-Bernstam F, Mills GB, Chen K. Zhou W, et al. Among authors: chen k, chen t. Bioinformatics. 2014 Apr 15;30(8):1073-1080. doi: 10.1093/bioinformatics/btt771. Epub 2014 Jan 2. Bioinformatics. 2014. PMID: 24389657 Free PMC article.
Clinical actionability enhanced through deep targeted sequencing of solid tumors.
Chen K, Meric-Bernstam F, Zhao H, Zhang Q, Ezzeddine N, Tang LY, Qi Y, Mao Y, Chen T, Chong Z, Zhou W, Zheng X, Johnson A, Aldape KD, Routbort MJ, Luthra R, Kopetz S, Davies MA, de Groot J, Moulder S, Vinod R, Farhangfar CJ, Shaw KM, Mendelsohn J, Mills GB, Eterovic AK. Chen K, et al. Among authors: chen t. Clin Chem. 2015 Mar;61(3):544-53. doi: 10.1373/clinchem.2014.231100. Epub 2015 Jan 27. Clin Chem. 2015. PMID: 25626406 Free PMC article.
novoBreak: local assembly for breakpoint detection in cancer genomes.
Chong Z, Ruan J, Gao M, Zhou W, Chen T, Fan X, Ding L, Lee AY, Boutros P, Chen J, Chen K. Chong Z, et al. Among authors: chen j, chen k, chen t. Nat Methods. 2017 Jan;14(1):65-67. doi: 10.1038/nmeth.4084. Epub 2016 Nov 28. Nat Methods. 2017. PMID: 27892959 Free PMC article.
TransVar: a multilevel variant annotator for precision genomics.
Zhou W, Chen T, Chong Z, Rohrdanz MA, Melott JM, Wakefield C, Zeng J, Weinstein JN, Meric-Bernstam F, Mills GB, Chen K. Zhou W, et al. Among authors: chen k, chen t. Nat Methods. 2015 Nov;12(11):1002-3. doi: 10.1038/nmeth.3622. Nat Methods. 2015. PMID: 26513549 Free PMC article. No abstract available.
ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.
Liu J, Cho SN, Akkanti B, Jin N, Mao J, Long W, Chen T, Zhang Y, Tang X, Wistub II, Creighton CJ, Kheradmand F, DeMayo FJ. Liu J, et al. Among authors: chen t. Cell Rep. 2015 Mar 10;10(9):1599-1613. doi: 10.1016/j.celrep.2015.02.014. Epub 2015 Mar 5. Cell Rep. 2015. PMID: 25753424 Free PMC article.
A global reference for human genetic variation.
1000 Genomes Project Consortium; Auton A, Brooks LD, Durbin RM, Garrison EP, Kang HM, Korbel JO, Marchini JL, McCarthy S, McVean GA, Abecasis GR. 1000 Genomes Project Consortium, et al. Nature. 2015 Oct 1;526(7571):68-74. doi: 10.1038/nature15393. Nature. 2015. PMID: 26432245 Free PMC article.
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