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Selective targeting of visceral adiposity by polycation nanomedicine.
Wan Q, Huang B, Li T, Xiao Y, He Y, Du W, Wang BZ, Dakin GF, Rosenbaum M, Goncalves MD, Chen S, Leong KW, Qiang L. Wan Q, et al. Among authors: chen s. Nat Nanotechnol. 2022 Dec;17(12):1311-1321. doi: 10.1038/s41565-022-01249-3. Epub 2022 Dec 1. Nat Nanotechnol. 2022. PMID: 36456644
Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.
Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H, de Stanchina E, Gershon MD, Grikscheit TC, Chen S, Studer L. Fattahi F, et al. Among authors: chen s. Nature. 2016 Mar 3;531(7592):105-9. doi: 10.1038/nature16951. Epub 2016 Feb 10. Nature. 2016. PMID: 26863197 Free PMC article.
Human organoid models to study SARS-CoV-2 infection.
Han Y, Yang L, Lacko LA, Chen S. Han Y, et al. Among authors: chen s. Nat Methods. 2022 Apr;19(4):418-428. doi: 10.1038/s41592-022-01453-y. Epub 2022 Apr 8. Nat Methods. 2022. PMID: 35396481 Review.
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Among authors: chen hj, chen s. Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28. Nature. 2021. PMID: 33116299 Free PMC article.
Male germ cells support long-term propagation of Zika virus.
Robinson CL, Chong ACN, Ashbrook AW, Jeng G, Jin J, Chen H, Tang EI, Martin LA, Kim RS, Kenyon RM, Do E, Luna JM, Saeed M, Zeltser L, Ralph H, Dudley VL, Goldstein M, Rice CM, Cheng CY, Seandel M, Chen S. Robinson CL, et al. Among authors: chen s, chen h. Nat Commun. 2018 May 29;9(1):2090. doi: 10.1038/s41467-018-04444-w. Nat Commun. 2018. PMID: 29844387 Free PMC article.
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells.
Ghazizadeh Z, Kao DI, Amin S, Cook B, Rao S, Zhou T, Zhang T, Xiang Z, Kenyon R, Kaymakcalan O, Liu C, Evans T, Chen S. Ghazizadeh Z, et al. Among authors: chen s. Nat Commun. 2017 Aug 21;8(1):298. doi: 10.1038/s41467-017-00129-y. Nat Commun. 2017. PMID: 28824164 Free PMC article.
Author Correction: A recellularized human colon model identifies cancer driver genes.
Chen HJ, Wei Z, Sun J, Bhattacharya A, Savage DJ, Serda R, Mackeyev Y, Curley SA, Bu P, Wang L, Chen S, Cohen-Gould L, Huang E, Shen X, Lipkin SM, Copeland NG, Jenkins NA, Shuler ML. Chen HJ, et al. Among authors: chen s. Nat Biotechnol. 2019 Jul;37(7):820. doi: 10.1038/s41587-019-0163-6. Nat Biotechnol. 2019. PMID: 31160724
Checkpoint kinase 2 controls insulin secretion and glucose homeostasis.
Chong ACN, Vandana JJ, Jeng G, Li G, Meng Z, Duan X, Zhang T, Qiu Y, Duran-Struuck R, Coker K, Wang W, Li Y, Min Z, Zuo X, de Silva N, Chen Z, Naji A, Hao M, Liu C, Chen S. Chong ACN, et al. Among authors: chen z, chen s. Nat Chem Biol. 2024 May;20(5):566-576. doi: 10.1038/s41589-023-01466-4. Epub 2023 Nov 9. Nat Chem Biol. 2024. PMID: 37945898 Free PMC article.
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