Chen S - Search Results

1

One-step generation of modular CAR-T cells with AAV-Cpf1.

Dai X, Park JJ, Du Y, Kim HR, Wang G, Errami Y, Chen S. Dai X, et al. Among authors: chen s. Nat Methods. 2019 Mar;16(3):247-254. doi: 10.1038/s41592-019-0329-7. Epub 2019 Feb 25. Nat Methods. 2019. PMID: 30804551 Free PMC article.

2

CRISPR-mediated direct mutation of cancer genes in the mouse liver.

Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. Xue W, et al. Among authors: chen s. Nature. 2014 Oct 16;514(7522):380-4. doi: 10.1038/nature13589. Epub 2014 Aug 6. Nature. 2014. PMID: 25119044 Free PMC article.

3

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.

Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, Platt RJ, Chen S. Chow RD, et al. Among authors: chen s. Nat Neurosci. 2017 Oct;20(10):1329-1341. doi: 10.1038/nn.4620. Epub 2017 Aug 14. Nat Neurosci. 2017. PMID: 28805815 Free PMC article.

4

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.

Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Wang G, et al. Among authors: chen s. Sci Adv. 2018 Feb 28;4(2):eaao5508. doi: 10.1126/sciadv.aao5508. eCollection 2018 Feb. Sci Adv. 2018. PMID: 29503867 Free PMC article.

5

Cancer CRISPR Screens In Vivo.

Chow RD, Chen S. Chow RD, et al. Among authors: chen s. Trends Cancer. 2018 May;4(5):349-358. doi: 10.1016/j.trecan.2018.03.002. Epub 2018 Mar 30. Trends Cancer. 2018. PMID: 29709259 Free PMC article. Review.

6

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion.

Chow RD, Kim HR, Chen S. Chow RD, et al. Among authors: chen s. Nat Commun. 2018 May 15;9(1):1903. doi: 10.1038/s41467-018-04158-z. Nat Commun. 2018. PMID: 29765043 Free PMC article.

7

Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo.

Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Codina A, et al. Among authors: chen s. Cell Syst. 2019 Feb 27;8(2):136-151.e7. doi: 10.1016/j.cels.2019.01.004. Epub 2019 Feb 20. Cell Syst. 2019. PMID: 30797773 Free PMC article.

8

In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens.

Chow RD, Wang G, Ye L, Codina A, Kim HR, Shen L, Dong MB, Errami Y, Chen S. Chow RD, et al. Among authors: chen s. Nat Methods. 2019 May;16(5):405-408. doi: 10.1038/s41592-019-0371-5. Epub 2019 Apr 8. Nat Methods. 2019. PMID: 30962622 Free PMC article.

9

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells.

Dong MB, Wang G, Chow RD, Ye L, Zhu L, Dai X, Park JJ, Kim HR, Errami Y, Guzman CD, Zhou X, Chen KY, Renauer PA, Du Y, Shen J, Lam SZ, Zhou JJ, Lannin DR, Herbst RS, Chen S. Dong MB, et al. Among authors: chen ky, chen s. Cell. 2019 Aug 22;178(5):1189-1204.e23. doi: 10.1016/j.cell.2019.07.044. Cell. 2019. PMID: 31442407 Free PMC article.

10

In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.

Ye L, Park JJ, Dong MB, Yang Q, Chow RD, Peng L, Du Y, Guo J, Dai X, Wang G, Errami Y, Chen S. Ye L, et al. Among authors: chen s. Nat Biotechnol. 2019 Nov;37(11):1302-1313. doi: 10.1038/s41587-019-0246-4. Epub 2019 Sep 23. Nat Biotechnol. 2019. PMID: 31548728 Free PMC article.

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