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Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk.
Kurilshikov A, van den Munckhof ICL, Chen L, Bonder MJ, Schraa K, Rutten JHW, Riksen NP, de Graaf J, Oosting M, Sanna S, Joosten LAB, van der Graaf M, Brand T, Koonen DPY, van Faassen M; LifeLines DEEP Cohort Study, BBMRI Metabolomics Consortium; Slagboom PE, Xavier RJ, Kuipers F, Hofker MH, Wijmenga C, Netea MG, Zhernakova A, Fu J. Kurilshikov A, et al. Among authors: chen l. Circ Res. 2019 Jun 7;124(12):1808-1820. doi: 10.1161/CIRCRESAHA.118.314642. Epub 2019 Apr 11. Circ Res. 2019. PMID: 30971183
Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas.
Liu J, Lahousse L, Nivard MG, Bot M, Chen L, van Klinken JB, Thesing CS, Beekman M, van den Akker EB, Slieker RC, Waterham E, van der Kallen CJH, de Boer I, Li-Gao R, Vojinovic D, Amin N, Radjabzadeh D, Kraaij R, Alferink LJM, Murad SD, Uitterlinden AG, Willemsen G, Pool R, Milaneschi Y, van Heemst D, Suchiman HED, Rutters F, Elders PJM, Beulens JWJ, van der Heijden AAWA, van Greevenbroek MMJ, Arts ICW, Onderwater GLJ, van den Maagdenberg AMJM, Mook-Kanamori DO, Hankemeier T, Terwindt GM, Stehouwer CDA, Geleijnse JM, 't Hart LM, Slagboom PE, van Dijk KW, Zhernakova A, Fu J, Penninx BWJH, Boomsma DI, Demirkan A, Stricker BHC, van Duijn CM. Liu J, et al. Among authors: chen l. Nat Med. 2020 Jan;26(1):110-117. doi: 10.1038/s41591-019-0722-x. Epub 2020 Jan 13. Nat Med. 2020. PMID: 31932804
Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity.
Chen L, Collij V, Jaeger M, van den Munckhof ICL, Vich Vila A, Kurilshikov A, Gacesa R, Sinha T, Oosting M, Joosten LAB, Rutten JHW, Riksen NP, Xavier RJ, Kuipers F, Wijmenga C, Zhernakova A, Netea MG, Weersma RK, Fu J. Chen L, et al. Nat Commun. 2020 Aug 11;11(1):4018. doi: 10.1038/s41467-020-17840-y. Nat Commun. 2020. PMID: 32782301 Free PMC article.
Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content.
Chen L, van den Munckhof ICL, Schraa K, Ter Horst R, Koehorst M, van Faassen M, van der Ley C, Doestzada M, Zhernakova DV, Kurilshikov A, Bloks VW, Groen AK; Human Functional Genomics Project; Riksen NP, Rutten JHW, Joosten LAB, Wijmenga C, Zhernakova A, Netea MG, Fu J, Kuipers F. Chen L, et al. Cell Rep. 2020 Oct 6;33(1):108212. doi: 10.1016/j.celrep.2020.108212. Cell Rep. 2020. PMID: 33027657 Free article.
Characterization of gut microbial structural variations as determinants of human bile acid metabolism.
Wang D, Doestzada M, Chen L, Andreu-Sánchez S, van den Munckhof ICL, Augustijn HE, Koehorst M, Ruiz-Moreno AJ, Bloks VW, Riksen NP, Rutten JHW, Joosten LAB, Netea MG, Wijmenga C, Zhernakova A, Kuipers F, Fu J. Wang D, et al. Among authors: chen l. Cell Host Microbe. 2021 Dec 8;29(12):1802-1814.e5. doi: 10.1016/j.chom.2021.11.003. Epub 2021 Nov 29. Cell Host Microbe. 2021. PMID: 34847370 Free article.
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