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Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.
Dogruluk T, Tsang YH, Espitia M, Chen F, Chen T, Chong Z, Appadurai V, Dogruluk A, Eterovic AK, Bonnen PE, Creighton CJ, Chen K, Mills GB, Scott KL. Dogruluk T, et al. Among authors: chen k, chen t, chen f. Cancer Res. 2015 Dec 15;75(24):5341-54. doi: 10.1158/0008-5472.CAN-15-1654. Epub 2015 Dec 1. Cancer Res. 2015. PMID: 26627007 Free PMC article.
Bias from removing read duplication in ultra-deep sequencing experiments.
Zhou W, Chen T, Zhao H, Eterovic AK, Meric-Bernstam F, Mills GB, Chen K. Zhou W, et al. Among authors: chen k, chen t. Bioinformatics. 2014 Apr 15;30(8):1073-1080. doi: 10.1093/bioinformatics/btt771. Epub 2014 Jan 2. Bioinformatics. 2014. PMID: 24389657 Free PMC article.
RET fusion as a novel driver of medullary thyroid carcinoma.
Grubbs EG, Ng PK, Bui J, Busaidy NL, Chen K, Lee JE, Lu X, Lu H, Meric-Bernstam F, Mills GB, Palmer G, Perrier ND, Scott KL, Shaw KR, Waguespack SG, Williams MD, Yelensky R, Cote GJ. Grubbs EG, et al. Among authors: chen k. J Clin Endocrinol Metab. 2015 Mar;100(3):788-93. doi: 10.1210/jc.2014-4153. Epub 2014 Dec 29. J Clin Endocrinol Metab. 2015. PMID: 25546157 Free PMC article.
Functional consequence of the MET-T1010I polymorphism in breast cancer.
Liu S, Meric-Bernstam F, Parinyanitikul N, Wang B, Eterovic AK, Zheng X, Gagea M, Chavez-MacGregor M, Ueno NT, Lei X, Zhou W, Nair L, Tripathy D, Brown PH, Hortobagyi GN, Chen K, Mendelsohn J, Mills GB, Gonzalez-Angulo AM. Liu S, et al. Among authors: chen k. Oncotarget. 2015 Feb 20;6(5):2604-14. doi: 10.18632/oncotarget.3094. Oncotarget. 2015. PMID: 25605252 Free PMC article.
Clinical actionability enhanced through deep targeted sequencing of solid tumors.
Chen K, Meric-Bernstam F, Zhao H, Zhang Q, Ezzeddine N, Tang LY, Qi Y, Mao Y, Chen T, Chong Z, Zhou W, Zheng X, Johnson A, Aldape KD, Routbort MJ, Luthra R, Kopetz S, Davies MA, de Groot J, Moulder S, Vinod R, Farhangfar CJ, Shaw KM, Mendelsohn J, Mills GB, Eterovic AK. Chen K, et al. Among authors: chen t. Clin Chem. 2015 Mar;61(3):544-53. doi: 10.1373/clinchem.2014.231100. Epub 2015 Jan 27. Clin Chem. 2015. PMID: 25626406 Free PMC article.
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