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R-loop-dependent promoter-proximal termination ensures genome stability.
Xu C, Li C, Chen J, Xiong Y, Qiao Z, Fan P, Li C, Ma S, Liu J, Song A, Tao B, Xu T, Xu W, Chi Y, Xue J, Wang P, Ye D, Gu H, Zhang P, Wang Q, Xiao R, Cheng J, Zheng H, Yu X, Zhang Z, Wu J, Liang K, Liu YJ, Lu H, Chen FX. Xu C, et al. Among authors: chen j, chen fx. Nature. 2023 Sep;621(7979):610-619. doi: 10.1038/s41586-023-06515-5. Epub 2023 Aug 9. Nature. 2023. PMID: 37557913 Free PMC article.
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells.
Gao X, Wang Q, Wang Y, Liu J, Liu S, Liu J, Zhou X, Zhou L, Chen H, Pan L, Chen J, Wang D, Zhang Q, Shen S, Xiao Y, Wu Z, Cheng Y, Chen G, Kubra S, Qin J, Huang L, Zhang P, Wang C, Moses RE, Lonard DM, Malley BWO, Fares F, Zhang B, Li X, Li L, Xiao J. Gao X, et al. Among authors: chen j, chen g, chen h. Nat Commun. 2020 Aug 6;11(1):3904. doi: 10.1038/s41467-020-17667-7. Nat Commun. 2020. PMID: 32764536 Free PMC article.
Author Correction: The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells.
Gao X, Wang Q, Wang Y, Liu J, Liu S, Liu J, Zhou X, Zhou L, Chen H, Pan L, Chen J, Wang D, Zhang Q, Shen S, Xiao Y, Wu Z, Cheng Y, Chen G, Kubra S, Qin J, Huang L, Zhang P, Wang C, Moses RE, Lonard DM, O' Malley BW, Fares F, Zhang B, Li X, Li L, Xiao J. Gao X, et al. Among authors: chen j, chen g, chen h. Nat Commun. 2020 Sep 23;11(1):4888. doi: 10.1038/s41467-020-18767-0. Nat Commun. 2020. PMID: 32968062 Free PMC article.
IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation.
Ni X, Xu Y, Wang W, Kong B, Ouyang J, Chen J, Yan M, Wu Y, Chen Q, Wang X, Li H, Gao X, Guo H, Cui L, Chen Z, Shi Y, Zhu R, Li W, Shi T, Wang LF, Huang J, Dong C, Lai Y. Ni X, et al. Among authors: chen j, chen z, chen q. Nat Immunol. 2022 Nov;23(11):1577-1587. doi: 10.1038/s41590-022-01339-3. Epub 2022 Oct 21. Nat Immunol. 2022. PMID: 36271146 Free PMC article.
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y, Liu T, Li L. Chen H, et al. Among authors: chen j, chen t, chen g. Exp Dermatol. 2017 Nov;26(11):1118-1124. doi: 10.1111/exd.13394. Epub 2017 Aug 30. Exp Dermatol. 2017. PMID: 28605165
BCL6 is regulated by the MAPK/ELK1 axis and promotes KRAS-driven lung cancer.
Li K, Liu Y, Ding Y, Zhang Z, Feng J, Hu J, Chen J, Lian Z, Chen Y, Hu K, Chen Z, Cai Z, Liu M, Pang X. Li K, et al. Among authors: chen j, chen z, chen y. J Clin Invest. 2022 Nov 15;132(22):e161308. doi: 10.1172/JCI161308. J Clin Invest. 2022. PMID: 36377663 Free PMC article.
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