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Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma.
Wang P, Zhao W, Sun J, Tao T, Chen X, Zheng YY, Zhang CH, Chen Z, Gao YQ, She F, Li YQ, Wei LS, Lu P, Chen CP, Zhou J, Wang DQ, Chen L, Shi XH, Deng L, ZhuGe R, Chen HQ, Zhu MS. Wang P, et al. J Allergy Clin Immunol. 2018 Apr;141(4):1259-1268.e11. doi: 10.1016/j.jaci.2017.05.053. Epub 2017 Jul 25. J Allergy Clin Immunol. 2018. PMID: 28754608
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