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H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Harutyunyan AS, Krug B, Chen H, Papillon-Cavanagh S, Zeinieh M, De Jay N, Deshmukh S, Chen CCL, Belle J, Mikael LG, Marchione DM, Li R, Nikbakht H, Hu B, Cagnone G, Cheung WA, Mohammadnia A, Bechet D, Faury D, McConechy MK, Pathania M, Jain SU, Ellezam B, Weil AG, Montpetit A, Salomoni P, Pastinen T, Lu C, Lewis PW, Garcia BA, Kleinman CL, Jabado N, Majewski J. Harutyunyan AS, et al. Among authors: chen h, chen ccl. Nat Commun. 2019 Mar 19;10(1):1262. doi: 10.1038/s41467-019-09140-x. Nat Commun. 2019. PMID: 30890717 Free PMC article.
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, Keogh MC, Bareke E, Djedid A, Harutyunyan AS, Jabado N, Garcia BA, Li H, Allis CD, Majewski J, Lu C. Weinberg DN, et al. Among authors: chen h, chen x. Nature. 2019 Sep;573(7773):281-286. doi: 10.1038/s41586-019-1534-3. Epub 2019 Sep 4. Nature. 2019. PMID: 31485078 Free PMC article.
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.
Krug B, Hu B, Chen H, Ptack A, Chen X, Gretarsson KH, Deshmukh S, Kabir N, Andrade AF, Jabbour E, Harutyunyan AS, Lee JJY, Hulswit M, Faury D, Russo C, Xu X, Johnston MJ, Baguette A, Dahl NA, Weil AG, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia BA, Soni RK, Gallo M, Taylor MD, Kleinman CL, Majewski J, Jabado N, Lu C. Krug B, et al. Among authors: chen h, chen x. bioRxiv [Preprint]. 2023 Nov 28:2023.11.28.567931. doi: 10.1101/2023.11.28.567931. bioRxiv. 2023. PMID: 38116029 Free PMC article. Preprint.
Integrating predictive coding and a user-centric interface for enhanced auditing and quality in cancer registry data.
Dai HJ, Chen CC, Mir TH, Wang TY, Wang CK, Chang YC, Yu SJ, Shen YW, Huang CJ, Tsai CH, Wang CY, Chen HJ, Weng PS, Lin YX, Chen SW, Tsai MJ, Juang SF, Wu SY, Tsai WT, Huang MY, Huang CJ, Yang CJ, Liu PZ, Huang CW, Huang CY, Wang WYC, Chong IW, Yang YH. Dai HJ, et al. Among authors: chen hj. Comput Struct Biotechnol J. 2024 Apr 7;24:322-333. doi: 10.1016/j.csbj.2024.04.007. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38690549 Free PMC article.
Asia-Pacific consensus on long-term and sequential therapy for osteoporosis.
Tai TW, Chen HY, Shih CA, Huang CF, McCloskey E, Lee JK, Yeap SS, Cheung CL, Charatcharoenwitthaya N, Jaisamrarn U, Kuptniratsaikul V, Yang RS, Lin SY, Taguchi A, Mori S, Li-Yu J, Ang SB, Chan DC, Chan WS, Ng H, Chen JF, Tu ST, Chuang HH, Chang YF, Chen FP, Tsai KS, Ebeling PR, Marin F, Nistal Rodríguez FJ, Shi H, Hwang KR, Kim KK, Chung YS, Reid IR, Chandran M, Ferrari S, Lewiecki EM, Hew FL, Ho-Pham LT, Nguyen TV, Nguyen VH, Lekamwasam S, Pandey D, Bhadada S, Chen CH, Hwang JS, Wu CH. Tai TW, et al. Among authors: chen hy. Osteoporos Sarcopenia. 2024 Mar;10(1):3-10. doi: 10.1016/j.afos.2024.02.001. Epub 2024 Mar 16. Osteoporos Sarcopenia. 2024. PMID: 38690538 Free PMC article. Review.
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