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Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication.
Guendel I, Iordanskiy S, Van Duyne R, Kehn-Hall K, Saifuddin M, Das R, Jaworski E, Sampey GC, Senina S, Shultz L, Narayanan A, Chen H, Lepene B, Zeng C, Kashanchi F. Guendel I, et al. Among authors: chen h. J Virol. 2014 Jan;88(2):1189-208. doi: 10.1128/JVI.01940-13. Epub 2013 Nov 13. J Virol. 2014. PMID: 24227837 Free PMC article.
Effect of transcription peptide inhibitors on HIV-1 replication.
Van Duyne R, Cardenas J, Easley R, Wu W, Kehn-Hall K, Klase Z, Mendez S, Zeng C, Chen H, Saifuddin M, Kashanchi F. Van Duyne R, et al. Among authors: chen h. Virology. 2008 Jul 5;376(2):308-22. doi: 10.1016/j.virol.2008.02.036. Epub 2008 May 2. Virology. 2008. PMID: 18455747 Free article.
Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.
Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, Zeng C, Kovalskyy D, El Kouni MH, Lepene B, Patanarut A, Nekhai S, Price DH, Kashanchi F. Van Duyne R, et al. Among authors: chen h. J Mol Biol. 2013 Feb 22;425(4):812-29. doi: 10.1016/j.jmb.2012.12.005. Epub 2012 Dec 13. J Mol Biol. 2013. PMID: 23247501 Free PMC article.
Break CDK2/Cyclin E1 interface allosterically with small peptides.
Chen H, Zhao Y, Li H, Zhang D, Huang Y, Shen Q, Van Duyne R, Kashanchi F, Zeng C, Liu S. Chen H, et al. PLoS One. 2014 Oct 7;9(10):e109154. doi: 10.1371/journal.pone.0109154. eCollection 2014. PLoS One. 2014. PMID: 25290691 Free PMC article.
Process-based network decomposition reveals backbone motif structure.
Wang G, Du C, Chen H, Simha R, Rong Y, Xiao Y, Zeng C. Wang G, et al. Among authors: chen h. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10478-83. doi: 10.1073/pnas.0914180107. Epub 2010 May 24. Proc Natl Acad Sci U S A. 2010. PMID: 20498084 Free PMC article.
De novo design of a beta alpha beta motif.
Liang H, Chen H, Fan K, Wei P, Guo X, Jin C, Zeng C, Tang C, Lai L. Liang H, et al. Among authors: chen h. Angew Chem Int Ed Engl. 2009;48(18):3301-3. doi: 10.1002/anie.200805476. Angew Chem Int Ed Engl. 2009. PMID: 19347908
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