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Expanding the use of arsenic trioxide: leukemias and beyond.
Chen Z, Chen GQ, Shen ZX, Sun GL, Tong JH, Wang ZY, Chen SJ. Chen Z, et al. Among authors: chen sj, chen gq. Semin Hematol. 2002 Apr;39(2 Suppl 1):22-6. doi: 10.1053/shem.2002.33611. Semin Hematol. 2002. PMID: 12012319 Review.
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins.
Chen GQ, Zhu J, Shi XG, Ni JH, Zhong HJ, Si GY, Jin XL, Tang W, Li XS, Xong SM, Shen ZX, Sun GL, Ma J, Zhang P, Zhang TD, Gazin C, Naoe T, Chen SJ, Wang ZY, Chen Z. Chen GQ, et al. Among authors: chen z, chen sj. Blood. 1996 Aug 1;88(3):1052-61. Blood. 1996. PMID: 8704214 Free article.
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells.
Chen GQ, Shi XG, Tang W, Xiong SM, Zhu J, Cai X, Han ZG, Ni JH, Shi GY, Jia PM, Liu MM, He KL, Niu C, Ma J, Zhang P, Zhang TD, Paul P, Naoe T, Kitamura K, Miller W, Waxman S, Wang ZY, de The H, Chen SJ, Chen Z. Chen GQ, et al. Among authors: chen z, chen sj. Blood. 1997 May 1;89(9):3345-53. Blood. 1997. PMID: 9129041 Free article.
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients.
Shen ZX, Chen GQ, Ni JH, Li XS, Xiong SM, Qiu QY, Zhu J, Tang W, Sun GL, Yang KQ, Chen Y, Zhou L, Fang ZW, Wang YT, Ma J, Zhang P, Zhang TD, Chen SJ, Chen Z, Wang ZY. Shen ZX, et al. Among authors: chen z, chen sj, chen gq, chen y. Blood. 1997 May 1;89(9):3354-60. Blood. 1997. PMID: 9129042 Free article. Clinical Trial.
Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients.
Niu C, Yan H, Yu T, Sun HP, Liu JX, Li XS, Wu W, Zhang FQ, Chen Y, Zhou L, Li JM, Zeng XY, Yang RR, Yuan MM, Ren MY, Gu FY, Cao Q, Gu BW, Su XY, Chen GQ, Xiong SM, Zhang TD, Waxman S, Wang ZY, Chen Z, Hu J, Shen ZX, Chen SJ. Niu C, et al. Among authors: chen z, chen sj, chen gq, chen y. Blood. 1999 Nov 15;94(10):3315-24. Blood. 1999. PMID: 10552940 Free article. Clinical Trial.
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia.
Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L, Huang Y, Zhang JW, Xiong SM, Chen SJ, Wang ZY, Chen Z, Chen GQ. Cai X, et al. Among authors: chen z, chen sj, chen gq. Leukemia. 2000 Feb;14(2):262-70. doi: 10.1038/sj.leu.2401650. Leukemia. 2000. PMID: 10673743
963 results