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Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S, Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele T, Vulimiri P, Way JM, Ross S. Sparks SM, et al. Among authors: chen g. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3100-3. doi: 10.1016/j.bmcl.2014.05.012. Epub 2014 May 16. Bioorg Med Chem Lett. 2014. PMID: 24881566
Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist.
Sparks SM, Aquino C, Banker P, Collins JL, Cowan D, Diaz C, Dock ST, Hertzog DL, Liang X, Swiger ED, Yuen J, Chen G, Jayawickreme C, Moncol D, Nystrom C, Rash V, Rimele T, Roller S, Ross S. Sparks SM, et al. Among authors: chen g. Bioorg Med Chem Lett. 2017 Mar 1;27(5):1278-1283. doi: 10.1016/j.bmcl.2017.01.034. Epub 2017 Jan 17. Bioorg Med Chem Lett. 2017. PMID: 28148462
Constitutive receptor systems for drug discovery.
Chen G, Jayawickreme C, Way J, Armour S, Queen K, Watson C, Ignar D, Chen WJ, Kenakin T. Chen G, et al. Among authors: chen wj. J Pharmacol Toxicol Methods. 1999 Dec;42(4):199-206. doi: 10.1016/s1056-8719(00)00075-7. J Pharmacol Toxicol Methods. 1999. PMID: 11033435
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