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Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Kumar B, Adebayo AK, Prasad M, Capitano ML, Wang R, Bhat-Nakshatri P, Anjanappa M, Simpson E, Chen D, Liu Y, Schilder JM, Colter AB, Maguire C, Temm CJ, Sandusky G, Doud EH, Wijeratne AB, Mosley AL, Broxmeyer HE, Nakshatri H. Kumar B, et al. Among authors: chen d. Sci Adv. 2022 Jan 14;8(2):eabh3375. doi: 10.1126/sciadv.abh3375. Epub 2022 Jan 12. Sci Adv. 2022. PMID: 35020422 Free PMC article.
TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer.
Khatpe AS, Dirks R, Bhat-Nakshatri P, Mang H, Batic K, Swiezy S, Olson J, Rao X, Wang Y, Tanaka H, Liu S, Wan J, Chen D, Liu Y, Fang F, Althouse S, Hulsey E, Granatir MM, Addison R, Temm CJ, Sandusky G, Lee-Gosselin A, Nephew K, Miller KD, Nakshatri H. Khatpe AS, et al. Among authors: chen d. Cancer Res. 2023 Apr 14;83(8):1345-1360. doi: 10.1158/0008-5472.CAN-22-3667. Cancer Res. 2023. PMID: 37057595 Free PMC article.
Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism.
Lancaster MS, Kim B, Doud EH, Tate MD, Sharify AD, Gao H, Chen D, Simpson E, Gillespie P, Chu X, Miller MJ, Wang Y, Liu Y, Mosley AL, Kim J, Graham BH. Lancaster MS, et al. Among authors: chen d. Cell Rep. 2023 Oct 31;42(10):113241. doi: 10.1016/j.celrep.2023.113241. Epub 2023 Oct 17. Cell Rep. 2023. PMID: 37819759 Free PMC article.
Signaling Pathway Alterations Driven by BRCA1 and BRCA2 Germline Mutations are Sufficient to Initiate Breast Tumorigenesis by the PIK3CAH1047R Oncogene.
Bhat-Nakshatri P, Khatpe AS, Chen D, Batic K, Mang H, Herodotou C, McGuire PC, Xuei X, Erdogan C, Gao H, Liu Y, Sandusky G, Storniolo AM, Nakshatri H. Bhat-Nakshatri P, et al. Among authors: chen d. Cancer Res Commun. 2024 Jan 5;4(1):38-54. doi: 10.1158/2767-9764.CRC-23-0330. Cancer Res Commun. 2024. PMID: 38059556 Free PMC article.
Author Correction: Lipid exposure activates gene expression changes associated with estrogen receptor negative breast cancer.
Yadav S, Virk R, Chung CH, Eduardo MB, VanDerway D, Chen D, Burdett K, Gao H, Zeng Z, Ranjan M, Cottone G, Xuei X, Chandrasekaran S, Backman V, Chatterton R, Khan SA, Clare SE. Yadav S, et al. Among authors: chen d. NPJ Breast Cancer. 2023 Mar 13;9(1):11. doi: 10.1038/s41523-023-00516-3. NPJ Breast Cancer. 2023. PMID: 36914690 Free PMC article. No abstract available.
31,465 results
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