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Proarrhythmic defects in Timothy syndrome require calmodulin kinase II.
Thiel WH, Chen B, Hund TJ, Koval OM, Purohit A, Song LS, Mohler PJ, Anderson ME. Thiel WH, et al. Among authors: chen b. Circulation. 2008 Nov 25;118(22):2225-34. doi: 10.1161/CIRCULATIONAHA.108.788067. Epub 2008 Nov 10. Circulation. 2008. PMID: 19001023 Free PMC article.
Calmodulin kinase II is required for fight or flight sinoatrial node physiology.
Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke W, Sarma S, Grumbach IM, Wehrens XH, Mohler PJ, Song LS, Anderson ME. Wu Y, et al. Among authors: chen b. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5972-7. doi: 10.1073/pnas.0806422106. Epub 2009 Mar 10. Proc Natl Acad Sci U S A. 2009. PMID: 19276108 Free PMC article.
T-tubule remodeling during transition from hypertrophy to heart failure.
Wei S, Guo A, Chen B, Kutschke W, Xie YP, Zimmerman K, Weiss RM, Anderson ME, Cheng H, Song LS. Wei S, et al. Among authors: chen b. Circ Res. 2010 Aug 20;107(4):520-31. doi: 10.1161/CIRCRESAHA.109.212324. Epub 2010 Jun 24. Circ Res. 2010. PMID: 20576937 Free PMC article.
PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes.
Wu CY, Jia Z, Wang W, Ballou LM, Jiang YP, Chen B, Mathias RT, Cohen IS, Song LS, Entcheva E, Lin RZ. Wu CY, et al. Among authors: chen b. PLoS One. 2011;6(9):e24404. doi: 10.1371/journal.pone.0024404. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912691 Free PMC article.
Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.
Xie YP, Chen B, Sanders P, Guo A, Li Y, Zimmerman K, Wang LC, Weiss RM, Grumbach IM, Anderson ME, Song LS. Xie YP, et al. Among authors: chen b. Hypertension. 2012 Feb;59(2):355-62. doi: 10.1161/HYPERTENSIONAHA.111.180968. Epub 2011 Dec 27. Hypertension. 2012. PMID: 22203744 Free PMC article.
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