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A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.
Zou H, Poore B, Brown EE, Qian J, Xie B, Asimakidou E, Razskazovskiy V, Ayrapetian D, Sharma V, Xia S, Liu F, Chen A, Guan Y, Li Z, Wanggou S, Saulnier O, Ly M, Fellows-Mayle W, Xi G, Tomita T, Resnick AC, Mack SC, Raabe EH, Eberhart CG, Sun D, Stronach BE, Agnihotri S, Kohanbash G, Lu S, Herrup K, Rich JN, Gittes GK, Broniscer A, Hu Z, Li X, Pollack IF, Friedlander RM, Hainer SJ, Taylor MD, Hu B. Zou H, et al. Among authors: chen a. Nat Cell Biol. 2023 Mar;25(3):493-507. doi: 10.1038/s41556-023-01093-0. Epub 2023 Feb 27. Nat Cell Biol. 2023. PMID: 36849558 Free PMC article.
Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models.
Chen A, Chao Y, Zou H, McCarl LH, Kohanbash G, Hu B. Chen A, et al. STAR Protoc. 2023 Mar 17;4(1):102049. doi: 10.1016/j.xpro.2023.102049. Epub 2023 Jan 19. STAR Protoc. 2023. PMID: 36861832 Free PMC article.
Understanding the glioblastoma (GBM) immune microenvironment and development of clinical treatment drugs rely on suitable preclinical GBM models. Here, we present a protocol to establish syngeneic orthotopic glioma mouse models. ...For complete details on the use and execu …
Understanding the glioblastoma (GBM) immune microenvironment and development of clinical treatment drugs rely on suitable preclinical GBM mo …
Development of a human glioblastoma model using humanized DRAG mice for immunotherapy.
Srivastava R, Labani-Motlagh A, Chen A, Bohorquez JA, Qin B, Dodda M, Yang F, Ansari D, Patel S, Ji H, Trasti S, Chao Y, Patel Y, Zou H, Hu B, Yi G. Srivastava R, et al. Among authors: chen a. Antib Ther. 2023 Oct 4;6(4):253-264. doi: 10.1093/abt/tbad021. eCollection 2023 Oct. Antib Ther. 2023. PMID: 38075240 Free PMC article.
TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro.
Singh SK, Wang Y, Habib A, Priyadarshini M, Kodavali CV, Chen A, Ma W, Wang J, Hameed NUF, Hu B, Fuller GN, Kulich SM, Amankulor N, Colen RR, Edwards LA, Zinn PO. Singh SK, et al. Among authors: chen a. Front Oncol. 2023 Oct 10;13:1279806. doi: 10.3389/fonc.2023.1279806. eCollection 2023. Front Oncol. 2023. PMID: 37881491 Free PMC article.
Chimeric antigen receptor T-cell infusion for large B-cell lymphoma in complete remission: a center for international blood and marrow transplant research analysis.
Wang TP, Ahn KW, Shadman M, Kaur M, Ahmed N, Bacher U, Cerny J, Chen A, Epperla N, Frigault M, Grover N, Haverkos B, Hill B, Hossain N, Iqbal M, Jain T, Krem MM, Maakaron J, Modi D, Alhaj Moustafa M, Riedell P, Savani B, Sica RA, Sureda A, Wudhikarn K, Herrera AF, Sauter C, Hamadani M, Jimenez Jimenez A. Wang TP, et al. Among authors: chen a. Leukemia. 2024 May 15. doi: 10.1038/s41375-024-02242-6. Online ahead of print. Leukemia. 2024. PMID: 38750138
Identification of Fibrinogen as a Plasma Protein Binding Partner for Lecanemab Biosimilar IgG: Implications for Alzheimer's Disease Therapy.
Bellier JP, Román Viera AM, Christiano C, Anzai JAU, Moreno S, Campbell EC, Godwin L, Li A, Chen AY, Alam S, Saba A, Yoo HB, Yang HS, Chhatwal JP, Selkoe DJ, Liu L. Bellier JP, et al. Among authors: chen ay. bioRxiv [Preprint]. 2024 May 1:2024.05.01.591892. doi: 10.1101/2024.05.01.591892. bioRxiv. 2024. PMID: 38746192 Free PMC article. Preprint.
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